The study indicated the beneficial effects of TQ in immune-related diseases, however, well designed clinical trials in humans are required to confirm these effects.
Our study has shown that carbomer 940 hydrogel is a nontoxic biomaterial, which improved tissue perfusion and decreased the area of necrotic tissue in burn wounds. Application of this biomaterial in treatment of burn injuries deserves further studies.
The present review purposed that although the experimental studies indicated the beneficial effects of TQ against liver diseases, more designed clinical trials in human are needed to confirm the safety and efficacy of TQ.
Chronic non-bacterial prostatitis (CNP) is the most common type of prostatitis and oxidative stress (OS) was shown to be highly elevated in prostatitis patients. This study aimed to investigate the protective effect of pentoxifylline (PTX) on CNP induced by carrageenan in rats. Male adult Wistar rats (n = 30) were divided into control, CNP and three treatment groups (n = 6) including CNP + cernilton and CNP + PTX groups. CNP was induced by single intraprostatic injection of 1% carrageenan (100 µl). Rats in treatment groups received orally cernilton 100 mg/kg and PTX at 50 and 100 mg/kg 1 week after CNP induction for 21 days. Prostatic index (PI), prostatic specific antigen (PSA), tumor-necrosis factor alpha (TNF-α), serum lipid peroxidation (MDA), blood urea nitrogen, creatinine and histopathological changes were compared between groups. There were significant increase of PI, serum levels of PSA, TNF-α and MDA in CNP group at 29 day. In treatment groups, significant reduction in PI, serum levels of PSA, TNF-α, MDA and creatinine was observed especially in rats treated with dose of 50 mg/kg of PTX. In CNP group, histopathological changes of the prostate such as leucocyte infiltration, large involutions and projection into the lumen and reducing the volume of the lumen were observed as well. Whereas PTX, especially at dose of 50 mg/kg, could improve the above-mentioned changes remarkably in CNP treated rats. For the first time, our findings indicated that PTX improved CNP induced by carrageenan in rats.
A common myna (Acridotheres tristis) was presented to Veterinary Teaching Hospital, School of Veterinary Medicine, Tehran University after swallowing a needle. Radiography and physical examination revealed a metal foreign body within the body with its distal end in the ventriculus. Surgical removal by ventriculotomy under general anesthesia was attempted. Six months of follow up study revealed no complications.
This report describes the clinical presentation, diagnosis and treatment of a queen with open pyometra. Lethargy, anorexia and previous treatment failure were the main reasons resulting in referral for diagnostic evaluation. The history, haematological and biochemical profiles and abdominal radiographs revealed open pyometra. Following ovariohysterectomy and antibiotic therapy there was total resolution of clinical signs. Histopathology of the uterus showed severe calcification. The unique part of this report was the rare appearance of multiple opacities in the radiographs. To the authors' knowledge, this is the first report of radiographic opacities in a domestic short-haired queen with open pyometra.Keywords: queen; pyometra; radiology; uterus; calcification Pyometra is the most frequent and important endometrial disorder in intact, sexually mature queens and is characterised by uterine infection by ascending vaginal bacteria as a consequence of progesterone stimulation of the endometrium. It may involve diffuse or segmental enlargement of the uterus. Histological lesions range from simple cystic endometrial hyperplasia to endometrial atrophy (Nak et al. 2009).Pyometra is classified as open-cervix or closedcervix based on cervical patency for drainage of purulent uterine fluid. Although medical management may be attempted, surgical intervention to prevent uterine rupture and septicaemia is the treatment of choice for any open-cervix pyometra where the bitch is systemically ill, or any case of closed-cervix pyometra (Adamovich-Rippe et al. 2013).In this paper, we describe an unusual feature of open pyometra in a queen, and its radiographic and histopathological change. Case descriptionA 4.3 kg, approximately six-year-old sexually intact female Domestic short-haired cat was presented to the Small Animal Hospital, University of Tehran, Tehran, Iran because of a history of anorexia and lethargy. The cat had lived indoors for approximately five years and had not been bred during this period of time. Two weeks prior to presentation she had the same clinical signs (lethargy and anorexia) and the owner referred her to a private pet clinic. The veterinarian prescribed antibiotics and intravenous lactated Ringer's solution, which initially resulted in improvement before a subsequent return of the clinical symptoms.On initial physical examination, the cat was mildly dehydrated and lethargic. Rectal temperature was normal (38.1 °C) and no abnormalities in mucous membrane colour were noted. Heart and respiratory sounds and rates were normal. Vaginal discharge was not observed and abdominal palpation revealed no abnormal organs. Polyuria and polydipsia were noted by the owner.Diagnostic procedures included a complete blood count (CBC), serum biochemical profile and abdominal radiographs. The CBC showed mild nonregenerative normocytic normochromic anaemia, leucocytosis with neutrophilia and the presence of immature WBCs in a peripheral blood sample.
Borehole gravity sensing can be used in a number of applications to measure features around a well, including rock-type change mapping and determination of reservoir porosity. Quantum technology gravity sensors, based on atom interferometry, have the ability to offer increased survey speeds and reduced need for calibration. While surface sensors have been demonstrated in real world environments, significant improvements in robustness and reductions to radial size, weight, and power consumption are required for such devices to be deployed in boreholes. To realise the first step towards the deployment of cold atom-based sensors down boreholes, we demonstrate a borehole-deployable magneto-optical trap, the core package of many cold atom-based systems. The enclosure containing the magneto-optical trap itself had an outer radius of (60 ± 0.1) mm at its widest point and a length of (890 ± 5) mm. This system was used to generate atom clouds at 1 m intervals in a 14 cm wide, 50 m deep borehole, to simulate how in-borehole gravity surveys are performed. During the survey, the system generated, on average, clouds of (3.0 ± 0.1) × 105 87Rb atoms with the standard deviation in atom number across the survey observed to be as low as 8.9 × 104.
Background: Activation of inflammatory cells can cause more chemicals induced-hepatotoxicity.
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