Bioequivalence testing is the initial approach for the analysis of quantitative determination of drugs and their metabolism in biological samples. In this research work its applications was tested and reviewed under different sampling techniques. The basic concept of bioequivalence testing crossover design was used to make assessment of medicine for breast cancer methotrexate and tamoxifen. Effectiveness of methotrexate at initial stage was 2.38 and at advance stage it was 1.85 which means it was 43% effective at initial stage while 38% effective in advance stage. Effectiveness of tamoxifen at initial stage 3.19 at advance stage 3.68 which means it was 52% effective at initial stage while 57% effective in advance stage. The relation of bioequivalence testing and distance base inference was highlighted. An attempt was made to analyze the efficiency of both medicines at initial and advance stage of diagnostic of breast cancer.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.