Aim: To determine correlation of serum testosterone with low and high density lipoprotein in male type 2 Diabetics presenting at a tertiary care hospital of Sindh.  Methodology: A cross sectional study, Department of Biochemistry and Department of Medicine, Liaquat University Hospital from January 2018 to February 2019. One hundred male type 2 diabetics (cases) and one hundred age matched male (control) were selected through non – probability purposive sampling. Male diagnosed cases of DM belonging to 4th to 6th decade of life was included. Blood samples were collected by venesection and sera were squeezed by centrifugation and stored at – 20 0C in refrigerators. Testosterone was estimated by the ELISA (competitive immuno- assay) assay method and blood lipids - cholesterol, triglycerides (TAGs), LDLc and HDLc by colorimetric method. Pearson`s correlation was generated on Statistical software SPSS 21.0 version (IBM, Incorp, USA) for correlation of serum testosterone with lipids fractions (P≤0.05). Results: Age shows majority of male type 2 diabetics were in their 5th decade. We found low serum testosterone level (10.85±4.7 mmol/L) in cases compared to normal testosterone level (13.39±3.8 mmol/L) in control (P=0.0001). Pearson`s correlation shows inverse association with HDLc (r= -0.70) (P=0.0001) and positive association with LDLc (r= 0.670) (P=0.0001). Conclusion: We found low serum testosterone in male type 2 diabetics that showed negative correlation with high density lipoprotein (HDLc) and positive correlation with low density lipoprotein (LDLc).

Aim: To determine the correlation of HBA1c and serum cholesterol in diabetic patients. Methodology: This case control study was completed at the Biochemistry and Medicine Departments of Liaquat University Hospital Jamshoro from October 2015 to March 2016.Total number of study subject was 100 and they were divided into two groups. Group A (case group, n=50) comprises diagnosed T2DM subjects while group B (control group, n=50) consists of healthy normal subjects (HNS), healthy normal subjects with mean age 50±6.34 years. These subjects were assessed to find association of glycosylated hemoglobin with serum Cholesterol levels in Type-2 Diabetes mellitus patients. Those patients diagnosed asT2DM with age 30- 60years were included while those patients diagnosed as diabetic erectile dysfunction, diabetic nephropathy, diabetic renal failure, familial dyslipidemia, and hypercholesterolemia was excluded in this study. Blood specimens were collected from both groups aseptically then blood glucose, HbA1c, Blood cholesterol, were estimated. Written consent was taken by all subjects including in this study. Data was analyzed by SPSS version 21.0. P value ≤ 0.05 were considered significant. Results: The mean fasting blood sugar (FBS) of study participants of both groups was 162.74±25.42 mg/dL and 82.60±10.03 mg/dL respectively. The mean random blood sugar of both groups was 299.72±57.88 mg/dL and142.72±31.63 mg/dL respectively and mean glycosylated hemoglobin (HbA1C) of both groups was 8.40±1.27 and 5.75±0.24mg/dL respectively. The mean serum cholesterol values of DP and HNS were 7.05±1.02 and 5.74±1.45 mg/dl respectively. Conclusion: It was observed a positive correlation between HBA1c and serum cholesterol in type2 DM patients.

Objective: The objective of the current study is to determine the pattern of dermatological disorders and to find out their connection with different socioeconomically factors among students of the Medical College. Methodology: The Cross sectional observational study was carried out for the period of three months .The research instrument used was the well developed questionnaire. Results: The questionnaire was administered among total 350 students and the most participant age group was the > 22 and that was about 47.4% of the total sample size the more skin complication seen was the acne that was about 59.7%, in addition to this dandruff contributed very heavily to the hair complexities which makes about 35.7% of the sample. Conclusion: Skin infections especially the cosmetic are very common among the Medical students.