Benzyltriphenylphosphonium peroxodisulfate has been found to be an effective reagent for the oxidative deprotection of trimethylsilyl (TMS) and tetrahydropyranyl (THP) ethers, ethylene acetals and ketals to their corresponding carbonyl compounds in excellent yields. Selective oxidative deprotection of TMS ethers in the presence of THP ethers and ethylene acetals (ketals) makes this method a useful and practical procedure in organic synthesis.
N-Bromosuccinimide was found to efficiently catalyze the synthesis of highly functionalized, tetra-substituted furan derivatives in the one-pot reactions of but-2-ene-1,4-diones and acetoacetate esters in the presence of i-PrOH as solvent under mild and neutral conditions at 80-90?C for 3-7 h in high yields (87-94%).
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