Purpose: Numerous studies have reported that vitamin E plays a key role in nervous system development and neurotransmitter production.This study aimed to investigate changes in vitamin E intake in older adults with low cognitive performance using NHANES. Methods: In this cross-sectional study, we examined a sample of 2,255 American adults aged 60 and over between 2011 and 2014. We collected dietary data by averaging two recalls for dietary use to determine vitamin E intake. We assessed cognitive function using five tests and analyzed the association between these variables using a multivariate logistic regression model. Results: A total of 2255 participants aged ≥60 years from the National Health and Nutrition Examination Survey (NHANES) for the 2011-2014 cycle were included in the analysis. Vitamin E intake was negatively associated with cognitive function. In the Z-test, each 1 mg/day increase in dietary intake of vitamin E was associated with a 6% lower likelihood of severe cognitive performance in the fully fitted model (OR = 0.94, 95% CI: 0.91~0.97) The results did not change when exposure was analyzed as a categorical variable. Compared with Q1, Q4 reduced the risk of cognitive impairment by 53% in the z-test (OR = 0.47, 95% CI: 0.33~0.67).No significant statistical interaction between the variables was found Conclusions: An increased dietary intake of vitamin E has been associated with decreased cognitive impairment in individuals over 60 years old. The dose-response curve showed an L-shaped association between dietary vitamin E intake and cognitive decline in US adults, with an inflection point of approximately 9.296 mg/day.
Introduction: With mounting evidence, there is a postulation that Hepatitis B Infection may be a risk factor for atherosclerotic diseases. Abdominal aortic calcification (AAC) has been found to be significantly associated with subclinical atherosclerotic diseases. Our objective was to investigate the relationship between Hepatitis B core antibody and abdominal aortic calcification. Methods: In this cross-sectional observational study, data from the National Health and Nutrition Examination Survey (NHANES) conducted during 2013–2014 were utilized to investigate the relationship between Hepatitis B core antibody and AAC. The study used dual-energy X-ray absorptiometry to measure AAC and evaluated it using the Kauppila score system. The variable LBXHBC of the NHANES dataset was reviewed to identify patients with positive Hepatitis B core antibody. To assess the association between Hepatitis B core antibody and AAC, multivariate logistic regression mixed models and subgroup analyses were conducted. Results: The 2013–2014 data showed documentation of 288 patients with positive Hepatitis B core antibody. After adjusting for multiple variables, the multivariable odds ratios (95% CI) revealed that severe AAC was correlated with Hepatitis B infection (OR = 1.52, 95%CI [1 ~ 2.3]; p = 0.05), as opposed to the no Hepatitis B group. However, this association was not observed among individuals with mild AAC (OR = 1.22, 95%CI [0.9 ~ 1.65]; p = 0.205). Results were consistent in multiple subgroup and sensitivity analyses. Conclusions: Individuals who tested positive for Hepatitis B core antibody had a higher likelihood of severe AAC compared to those who tested negative, while no significant association was observed among individuals with mild AAC.
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