Objective. To explore and analyze the application effect of external and internal elevation of the maxillary sinus in implant restoration of the posterior maxilla. Methods. A total of 84 patients undergoing implant restoration of the posterior maxilla in the hospital were enrolled between January 2019 and March 2021. According to the random number table method, they were divided into the observation group (n = 42) and the control group (n = 42). The control group underwent external elevation of the maxillary sinus, while the observation group underwent internal elevation of the maxillary sinus. At 6 h, 12 h, and 24 h after surgery, the pain degree between the two groups was compared. All were followed up at 6 months after surgery. The osseointegration (bone resorption around implants, elevation height of maxillary sinus floor, average healing time) and soft tissues (bleeding index, plaque index, probing depth) in both groups were observed. The occurrence of postoperative complications was recorded. Results. At 6 h, 12 h, and 24 h after surgery, VAS scores in the observation group were significantly lower than those in the control group ( P < 0.05 ). At 6 months after surgery, bone resorption and elevation height of the maxillary sinus floor in the observation group were significantly higher than those i.0.0n the control group, and the average healing time was significantly shorter than that in the control group ( P < 0.05 ). The bleeding index, plaque index, and probing depth in the observation group were significantly lower than those in the control group ( P < 0.05 ). There was no significant difference in the incidence of postoperative complications between the observation group and the control group (9.52% vs. 19.05%) ( P > 0.05 ). Conclusion. The application effect of internal elevation of the maxillary sinus is good in implant restoration of the posterior maxilla, which can relieve pain and swelling and improve implant effect.
Background: Human papillomavirus (HPV) infection is closely correlated with cervical lesions. However, the HPV prevalence varies among different districts. This retrospective study investigated the HPV genotype distribution and its relationship with cervical lesions in southern Hunan Province.Methods: HPV and morphological examinations results from HPV-positive patients during 2018-2020 were reviewed. A total of 49,955 gynaecological inpatients and outpatients, each of whom underwent HPV testing, were included in this study. Available cytology and relevant histological examination results were reviewed. Furthermore, we limited the interval between HPV testing and the receipt of associated morphological results (if available) in the same patient to within 180 days to ensure their correlation when analysing their relationship.Results: The overall HPV positivity rate was 14.6%. The top five most prevalent HPV genotypes were HPV52, 16, 58, 53 and 51 (23.0%, 17.5%, 14.3%, 7.5%, and 6.0%, respectively). The HPV prevalence in the group aged ≤20 years was the highest, followed by the prevalence in the group aged 60–69 years. Single infection was the main type of HPV infection, and multiple infections occurred in 21.96% (1600/7286) of the infected women. Cytological and pathological abnormalities were mainly associated with infection with HPV16, 52 and 58. Further analysis found that HPV16, 58, 52 and 33 were the main genotypes associated with high-grade squamous lesions (HSIL) and that HPV16, 31, 33 and 58 were independent risk factors for HSIL (OR=1.70, 1.99, 2.59, 2.29; all P<0.05). HPV16, 58, 52, 18 and 33 were the most frequent genotypes detected in squamous cell carcinoma (SCC) patients, and HPV16 and 18 were independent risk factors for cervical carcinomas (OR=6.72, P<0.001; OR=1.67, P=0.001).Conclusion: This retrospective study demonstrated the prevalence and the distribution characteristics of HPV infection and its correlation with cervical lesions in southern Hunan Province. The comprehensive results of this survey can guide HPV vaccine research to protect against some common genotypes in China.
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