Objective: The title is research curative effect of intravascular low level laser irradiation (ILLLI) in treatment of psoriasis. Method: 478 patients with psoriasis from five groups to observe their efficacy. Group1 were treated by He-Ne laser combined with drug. Group 2 were treated by semi-conductor laser combined with drug. Group 3 were treated only by He-He laser. Group 4 were treated by semi-conductor laser. Group 5 were treated only by drug. The Ridit statistical analysis was applied to all of these data. The treatment of intravascular low level laser irradiation is as follow: laser power:4-5mw, 1 hour per day and 10 days as a period combined with vit C 2.0 g iv and inhalation of O2.
Results:The clinical results: the near efficient rate was 100%, in group1-4, if combined with drugs it would be better.Ridit statistical analysis showed no significant difference between group1-4, p>0.05. The efficient rate 72.97% in group5.There were showed very significant difference with group1-4, p<0.01. 2.There were no significant differences between He-Ne laser (632.8nm) and semiconductor laser(650nm); 3.The efficacy of ILLLI in psoriasis was positive correlation to the ILLLI times.Conclusions: It can improve curative effect of intravascular low levellaser irradiation (ILLLI) in treatment of psoriasis.
INTROCUCTIONPsoriasis is a kind of common chronic, recurrent and inflammatory hyperplastic dermatosis. The treatment of psoriasis becomes a knotty problem. After several recurrences the common therapy becomes invalid.Because of the obvious side effect and rebound phenomenon of immunosuppressors which have good curative effect, the doctors and patients are puzzled and treatment of psoriasis becomes a knotty problem. So to find a new safe and efficient treatment is the problem to be solved urgently in clinical dermatology now. Intravascular low level laser irradiation (ILLLI) is a new therapy rising in the recent years.We gave 404 patients ILLLI therapy combined with hormone and immnosuppressor from June 1995.Among them, 394 patients who suffered psoriasis vulgaris were in active phase, 6 suffered pustular psoriasis, 2 suffered psoriatic arthritis and 2 suffered erythroderma psoriaticum.. The recent therapeutic effects were satisfactory and obviously prior to control groups (74 patients only treated by drugs )
patients only treated with ILLLI
Subjects:There were 478 outpatients from our hospital in this group. Among them 254 were male and 224 were female. The age is from 5 to 68 years. The average age is 37.51±14.63 years. The course of disease is from 2 weeks to 30 years. The average course is 6.87 years. All except 6 patients with pustular psoriasis, 2 with psoriatic arthritis and 2 with
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