Infection with Helicobacter pylori (H. pylori) is common in developing countries such as Benin. This germ can cause several gastroduodenal diseases such as gastritis, ulcer, adenocarcinoma or gastric MALT lymphoma. This study aimed to determine the prevalence of H. pylori infection and gastric pre-neoplastic histological lesions in patients admitted for upper gastrointestinal endoscopy (UGE) and to identify factors associated with this infection.Methods: This was a cross-sectional descriptive and analytical study, with prospective data collection, conducted from October 2014 to December 2015. We included all patients admitted to Menontin Hospital for UGE in whom a gastric biopsy has been done. H. pylori research was conducted in anatomy-pathology, either in a medical laboratory in Cotonou or at the CERBA laboratory in Paris, France, depending on the patient's choice. The microscopic study was carried out after staining with Haematoxyline-Eosine-Safran (HES) and the search for H. pylori using Giemsa staining.Results: H. pylori was investigated in 137 patients, 67 men (48.9%) and 70 women (51.1%). The mean age was 48.3±14.6years with extremes of 10 and 83years. Some patients had had at least one previous H. pylori eradication treatment (63 cases or 46%). For the general population, the test was positive in 98 cases, i.e. a prevalence of 71.5%. Depending on whether or not patients had been pre-treated for H. pylori, the test was positive in 40 out of 63 (63.5%) pre-treated patients, versus 58 out of 74 (78.4%) patients who were naïve to any eradication treatment (p=0.057). The pre-neoplastic lesions noted were gastric atrophy in 35 patients (including 25 H. pylori positive), intestinal metaplasia in 13 patients (including 10 H. pylori positive) and low grade dysplasia in 14 patients (including 12 H. pylori positive); high grade dysplasia was found in one patient who was H. pylori negative. Only the type of prior eradicant treatment appeared to be associated with H. pylori infection (p=0.182).
Conclusion:H. pylori infection is common in our patients admitted for upper gastrointestinal endoscopy. Gastric atrophy was the most common pre-neoplastic lesion.
Introduction: Hanging is one of the most common methods of suicide. It can also be used to conceal a crime. Thus, it is important to systematically have a forensic autopsy performed in cases of hanging. Only that examination can determine the actual forensic form of the death. At the national level, there is no epidemiological data on suicide by hanging in Benin. Aims: This study aims to describe the epidemiological and forensic features observed in the cases of suicide by hanging in Benin. Material and Methods: This is a descriptive and retrospective study of all the suicidal deaths by hanging collated in the Forensic & Legal Medicine Unit of the Faculty of Health Sciences (UML_FSS) for a period of 12 years, 2005-2017, in Benin. Result: Suicides by hanging accounted for 8.3% of the cases of suspicious deaths autopsied in the south and center of Benin. Males represented 85.9% of the corpses, and most individuals were under 40 years old (62.0%). Hangings were complete in 65.4% of the cases. The material used most often for hanging (28.7% of cases) was nylon rope. Subcutaneous hemorrhages (46.2%) and ecchymosis in the sterno-cleido-mastoid muscles (61.3%) were the most common finding at the neck dissection.
Conclusion:Hanging is a common method of suicide, especially among young men. In Benin, it occurs behind closed doors and by means of tools used in everyday life. Forensic autopsies, however, remain infrequent in cases of suicides.
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