Paragangliome de la queue de cheval : à propos d’une série de 9 cas

Seidou, Falilatou; Tamarit, Clémence; Sevestre, Henri

doi:10.1016/j.annpat.2020.02.018

Cited by 2 publications

(4 citation statements)

References 15 publications

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“…The most common presenting symptom in a patient with a lumbo-sacral paraganglioma is lower back pain with radiculopathy [7,20,58,67]. Lower back pain was reported in 94% of the cases in our review.…”

Section: Discussionmentioning

confidence: 68%

“…The diagnostic procedure of choice for an intradural lesion is MRI, although it should be noted that the MRI findings are nonspecific for these lesions. Paragangliomas are usually isointense to spinal cord on T1-weighted images, hyperintense on T2-weighted images and enhance with gadolinium [15,54,58,67]. Whilst MRI gives accurate anatomical information regarding intradural cauda equina lesions, the differential diagnosis includes schwannoma, ependymoma, meningioma or solitary metastasis [23] and remains difficult to diagnose paraganglioma preoperatively based solely on the MRI findings.…”

Section: Discussionmentioning

confidence: 99%

“…4). We have included 51 [4,15,20,21,30,49,51,58,60,61,67,68,78] (Tables 2 and 3). The mean patients' age was 48.8 ± 1.2 (range 17-75 years).…”

Section: Patient Demographics and Presentationmentioning

confidence: 99%

“…The peak incidence is in the 5th decade, with male predominance [20,26,67]. The main anatomical spinal site is cauda equina and filum terminale [3,20,26,32,58,67].…”

Section: Introductionmentioning

confidence: 99%

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Paraganglioma of the cauda equina: a tertiary centre experience and scoping review of the current literature

et al. 2021

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Cauda equina paragangliomas are rare benign extra-adrenal neuroendocrine tumours arising from the neural crest cells associated with autonomic ganglia. These tumours are often mistaken preoperatively for ependymomas or schwannomas. Patients present with axial or radicular pain with or without neurological deficits. Recurrence, secretory features and length of follow-up are controversial. We conducted a retrospective cohort study of paraganglioma through searching a prospectively maintained histopathology database. Patient demographics, presentation, surgery, complications, recurrence, follow-up and outcome between 2004 and 2016 were studied. The primary aim was to collate and describe the current evidence base for recurrence and secretory features of the tumour. The secondary objective was to report outcome and follow-up strategy. A scoping review was performed in accordance with the PRISMA-ScR Checklist. Ten patients were diagnosed (M:F 7:3) with a mean age of 53.6 ± 5.1 (range 34–71 years). MRI scans revealed intradural lumbar enhancing lesions. All patients had complete microsurgical excisions without adjuvant therapy with no recurrence with a mean follow-up of 5.1 ± 1.4 years. Tumours were attached to the filum terminale. Electron microscopic images demonstrated abundant neurosecretory granules with no evidence of catecholamine production. A total of 620 articles were screened and 65 papers (including ours) combining 121 patients (mean age 48.8 and M:F 71:50) were included. The mean follow-up was 3.48 ± 0.46 (range 0.15–23 years). Back pain was the most common symptom (94%). Cure following surgery was achieved in 93% of the patients whilst 7% had recurrence. Total resection likely results in cure without the need for adjuvant therapy or prolonged follow-up. However, in certain situations, the length of follow-up should be determined by the treating surgeon.

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Section: Discussionmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 99%

“…4). We have included 51 [4,15,20,21,30,49,51,58,60,61,67,68,78] (Tables 2 and 3). The mean patients' age was 48.8 ± 1.2 (range 17-75 years).…”

Section: Patient Demographics and Presentationmentioning

confidence: 99%

“…The peak incidence is in the 5th decade, with male predominance [20,26,67]. The main anatomical spinal site is cauda equina and filum terminale [3,20,26,32,58,67].…”

Section: Introductionmentioning

confidence: 99%

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