Background: Colorectal Cancer (CRC) is the third most common cancer in Iran and its early detection is necessary. This study is based on perception of people in the east of Iran toward CRC screening. Methods: In a cross-sectional study, 1060 randomly selected individuals who referred to Razavi Hospital of Mashhad, Iran, between September the 1 st , 2012 and February the 28 th , 2013 as patients or their visitors involved in an interview to fill a questionnaire on CRC screening. Results: The participants' age ranged from 40 to 88 years (mean= 55). More than 90% had no knowledge of CRC and screening tests. The most cited reasons for not having screening tests were "did not have any problem" and "did not think it was needed". Although, older people had more knowledge of CRC (P= 0.033), there was no relationship between gender, health insurance status, family history of individuals and their knowledge about CRC (P> 0.050). Employment, education and higher income had positive effect on the perception of people toward CRC screening (P< 0.050). Conclusion: Lack of knowledge in people in lower socio-economical class with limited literacy is the most important barrier to CRC screening. As such, designing educational programs involving physicians and media is important to improve CRC screening rates.

IntroductionAccording to recent statistics, there has been a rapid growth of breast cancer in developing countries. Thus, early detection is essential. This study is based on the perception of people in the Northeast of Iran regarding breast cancer screening.MethodsIn a cross-sectional study, 1469 women were selected randomly in the period from April to November 2016. The study population consisted of women or their companions referring to outpatient clinics or people in public urban areas who filled out a breast cancer screening questionnaire in an interview.ResultsThe patients’ age was in the range of 14 to 84 years (mean = 38.8). More than 84% of interviewees were not informed of breast cancer and screening tests. The main reasons mentioned by patients for their failure to do screening tests was ‘absence of any symptom or problem’ and ‘they did not think it was necessary’.There was not a significant difference between income level, marital status and knowledge of people about breast cancer screening tests (P > 0.05). However, employment, education level and family history had a positive effect on people’s awareness of breast cancer and its screening tests (P < 0.05).ConclusionThe lack of knowledge in people from low socio-economic classes was the main barrier to breast cancer screening. In this regard, organizing training programs by physicians and the media can help raise screening rates.

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Context: Despite the improvements that have been made in treatment of breast cancer, upper-limb lymphedema is still an unsolved problem in the treatment of women with breast cancer. Upper extremity lymphedema may accompany with decreased in shoulder range of motion and strength, and also pain. Nowadays, exercise training acts as a treatment method to control lymphedema in breast cancer survivors. Therefore, this study reviews the results of the applied studies in this field to survey the influences of exercise training on lymphedema and to determine its related symptoms in women with breast cancer. Data Sources: Literature investigation was conducted on August 1st, 2016 using PUBMED, MEDLINE, CINAHL, and Google Scholar databases. Study Selection: Randomized and nonrandomized controlled trials published in English were included. Twelve trails met inclusion criteria. Data Extraction: Data were extracted in a standardized manner into the predefined table. Then, quality of the studies was evaluated using the guide to community preventive services tool. Conclusions: It can be seen that a few studies have examined the effect of exercise training on lymphedema to conduct a review study. So, lymphedema continues to be a problem for breast cancer survivors. According to most studies, aerobic, resistance and stretching training programs had no influence on the volume and circumference of arm in lymphedema cancer patients, but the training had a noticeable influence on quality of life

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Introduction: In this study we investigated epidemiology and trends of primary lung cancers in northeast of Iran during 1985-2012. Methods: In this cross-sectional study records of primary lung cancers from 1985 to 2012 in Mashhad, northeast of Iran, were investigated. Data were obtained from the referral oncologic hospital and private radiation oncology clinic. To study trends, the duration of study was categorized into three periods: 1985-1995, 1995-2005 and 2005-2012. Statistically significant level was considered &lt;0.05. Results: Of 939 cases with mean age of 60.57 (±12.31) years, 660(70.3%) were male. Male to female ratio was 2.36. Mean age was 61.47±12.01 years for males and 58.45±12.75 for females (p=0.001). Mean age at diagnosis and rate of smokers was unchanged in three intervals (table 1). Time period1985-19951995-20052005-20012P valueAge(years)60.67±11.7460.57±12.2460.49±12.940.98Gender:Male167(78.4)330(68.6)163(66.5)0.01female46(21.6)151(31.4)82(33.5Male to female ratio3.632.181.99Smoking history:Yes69(76.7)211(67.8)100(65)0.15no21(23.3)100(32.2)54(35)Smokers:Male59(85.5)159(75.4)74(74)0.16Female10(14.5)52(24.6)26(26)Male-to-female ratio of smokers5.93.062.84 Squamous cell carcinoma with relative frequency of 44.2% was the most frequent pathologic subtype in total population followed by adenocarcinoma (18.2%), Small Cell Lung cancer (16.8%), large Cell carcinoma (1.3%) and other subtypes (19.5%). Relative frequency of pathologic subtypes had significant changes in three intervals (p &lt;0.001). Relative frequency of adenocarcinoma and large cell carcinoma were increasing while it was decreasing for SCC and SCLCs during three recent decades. There was statistically significant difference in mean age at diagnosis (p&lt;0.001), rate of smokers (p&lt;0.001) and male to female ratio (p=0.01) between four leading pathologic subtypes. Mean age at diagnosis (55.92±12.90 years), male to female ratio (1.69), and rate of smokers (46.8%) were lowest in adenocarcinomas. Conclusion: Similar to universal picture, adenocarcinoma showed increasing rates during recent three decades with higher prevalence among younger aged patients, women and nonsmokers. These trends are indicative of changes in exposures and smoking habits and reveal the need for regional studies in this context. Citation Format: Maryam Salehi, Pardis Shojaee, Soodabeh Shahidsales, Seyed Amir Aledavood, Mehdi Seilaniantoosi, Golboo Goshayeshi, Fahimeh Khoshroo. Epidemiology of primary lung cancer and its trend northeast of Iran during 1985-2012 [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 263. doi:10.1158/1538-7445.AM2017-263