<p class="abstract"><strong><span lang="EN-US">Background: </span></strong>The study attempts to investigate the effect of PEMF therapy on Refractory Migraines (RM), both those which were related and those which were not related to menstrual cycle, in a randomized, single blind, placebo-controlled study.</p><p class="abstract"><strong><span lang="EN-US">Methods: </span></strong>The study attempts to investigate the effect of PEMF therapy on Refractory Migraines (RM), both those which were related and those which were not related to menstrual cycle, in a randomized, single blind, placebo-controlled study.</p><p class="abstract"><strong><span lang="EN-US">Results: </span></strong>There was a significant improvement for the active group in terms of their headache days, durations and work-loss hours due to headache compared to the placebo group after 2 weeks. The added results of the assessment of the active group indicated a significant improvement in the days and duration of headaches, work-loss hours and number of medications even after a following 4-8-month period. Headache intensity and the amount of medication used for headache were reduced only in RM patients that had headaches which were not related to their menstrual cycles.</p><p class="abstract"><strong><span lang="EN-US">Conclusions:</span></strong><span lang="EN-US"> PEMF (10 Hz, 4-5mT) can be considered as a beneficial and persistent prophylactic treatment option for refractory migraine.</span></p>
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