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AMT is a safe method for ocular surface reconstruction with a very low rate of microbial infections, especially if AM is prepared according to Good Tissue Banking Practice set forth by FDA. Gram-positive isolates seem to be the most frequent isolates in infections after AMT.

There is a delay in starting microbiologic-guided antibiotic treatment in patients who have received empiric therapy. Nonbacterial corneal pathogens may be associated more frequently with patients on prior therapy.