The clinical and pathologic findings in eleven cases of parapharyngeal space tumors are described. The anatomy of this area and diagnostic procedures are discussed. Investigations should include a few basic examinations such as sialogram-computed tomographic (CT) scan, carotid angiogram, and echography. Several surgical approaches are considered in relation to the site and the size of the neoplasm. Prognosis depends on the histologic type of the tumor.

The first case of the association of oat cell carcinoma and squamous carcinoma of the hypopharynx occurring in a 57-year-old man is reported. The patient underwent total laryngopharyngectomy with radical neck dissection, but died 3¹/₂ months after diagnosis with multiple bone metastases of the ribs and vertebrae. The histogenesis of oat cell carcinoma in the hypopharynx is discussed, together with the therapeutic approach for the simultaneous occurrence of two primary malignant neoplasms in the same organ.

No abstract

No abstract

An exceptional case of pleomorphic malignant fibrous histiocytoma of the larynx occurring in a 68-year-old male patient is reported. A significant histological documentation is given. Problems connected with histogenesis, treatment and prognosis are dealt with. Stress is laid on the need to establish differential diagnosis from other neoplasms, in particular liposarcoma and spindle-cell carcinoma.