The erythrocyte sedimentation rate (ESR) correlated significantly with the total urinary protein (TUP) in 24-hour urine collections in patients with glomerular disease (p < 0.05 to p < 0.001). The relationship was linear for all patients with a glomerular process but no longer held true once the patients were treated with immunosuppressives, or when the underlying disease excluded the glomerulus. The association between ESR and TUP was generally of the magnitude ESR = TUP X 10. ESR was not correlated with creatinine clearance.
A retrospective review of hepatitis B serologies from 6,686 patients was conducted to determine the incidence of loss of antibody to hepatitis B surface antigen (anti-HBs) with retention of antibody to the core antigen of hepatitis B virus (anti-HBc) activity. In a subgroup of 48 multiply tested patients who were presumed to have resolved their acute or subacute hepatitis B virus infection, 9 (19%) were found to have lost anti-HBs while retaining anti-HBc activity.
A 21‐year‐old man who developed heavy proteinuria 8 years after remission of Hodgkin's disease treated with MOPP chemotherapy and radiation therapy is reported. Evidence of Hodgkin's disease could not be documented, and minimal changes were revealed by renal biopsy. Proteinuria persisted for 20 months and was followed by dysuria and the discovery of an inflammatory polyp of the bladder. The proteinuria decreased 1 month after excision of the polyp, and disappeared during the following year. Rather than indicating relapse of lymphoma, proteinuria in this patient resulted from a lesion not previously associated with Hodgkin's disease, but possibly resulting from long‐term effects of therapy.
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