Residual confounding by a matching variable and different definitions of the exposure time window explained differences in results. In case-control studies of drug use and fracture risk, broad matching criteria for age should be avoided and the selection of the time-window for exposure should be carefully considered.

In addition to after-laying of new-installed high voltage (HV) power cables the use of on-site non-destructive on-site testing and diagnosis of service aged power cables is becoming an important issue to determine the actual condition of the cable systems and to determine the future performances. In this paper based on field experience an overview is presented on on-site testing and partial discharge diagnosis of HV power cables with regard to on-site testing methods: energizing, diagnostic aspects, possibilities and implications for new and service aged power cables.

Background: Poor adherence to antihypertensives is associated with negative outcome of the disease as well as loss of health-care resources. Addressing the epidemic of poor adherence requires identifying factors associated with this behaviour. The aim of this study is to describe adherence to antihypertensive medication among Lebanese hypertensive patients and to evaluate the association between socioeconomic , patient-and conditionsrelated factors and non-adherence. Methods: A cross-sectional study was carried out on adherence to antihypertensive medications covering all governorates of Lebanon. This study was conducted between February 2018 and January 2019 on a random sample of 1497 hypertensive patients. A faceto-face questionnaire was used to assess adherence to antihypertensive medication and its determinants according to the five World Health Organization (WHO) main categories. Logistic regression analysis was performed to test the adjusted association between the multiple exposure factors, and drug adherence data were collected by trained interviewers. Results: Adherence to antihypertensive medications was reported by 1253 (83.7%) of the patients. After multivariate analysis, patients who tried to control their stress level (OR = 0.77, 95% CI [0.38-0.95]), those who had normal BP readings (OR =0.49, 95% CI [0.18-0.97]), and those who believed in the effectiveness of their treatment (OR = 0.31, 95% CI [0.14-0.76]) had a significantly lower chance to exhibit non-adherence to their treatment. However, older patients (OR= 1.87, 95% CI [1.23-2.21]), divorced/separated patients (OR= 2.14, 95% CI [1.31-5.48]), married (OR=1.96, 95% CI [1.27-3.90]), widowed (OR=2.11, 95% CI [1.62-6.50]), obese patients (OR = 1.76, 95% CI [1.21-1.94]), and patients who smoked hookah and cigarettes (OR = 2.62, 95% CI [1.17-6.76]) were more likely to exhibit non-adherence. Conclusion: Our study highlights the influence of factors such as old age, marital status, BMI and high level of emotional stress on non-adherence to medication in hypertensive patients. These determinants should be incorporated into adherence improving strategies.

A previous chlamydia infection did not result in fewer pregnant women, but among women with a pregnancy intention, time to pregnancy was longer compared with women without a previous infection. Supplemental digital content is available in the text.

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IntroductionThe aim of this systematic review was to evaluate the difference between a traditional meta-analysis and a mega-analysis of individual patient data when combining observational studies. Materials and methodsWe used data from two studies that evaluated the risk of fracture in patients with multiple sclerosis using the British General Practice Research Database and the Danish National Health Registries. The published results were pooled together in an inverse-variance fixed effect metaanalysis. Using patient level data, we made the study populations as comparable as possible regarding the index date, calendar time, selection of incident/prevalent patient and follow-up. The individual patient data of these populations were combined