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Expérience GANIL/SPIRAL/MUST2/E525SThe low-lying spectroscopy of 6He was investigated via the 2-neutron transfer reaction p(8He, t) with the 8He beam delivered by the SPIRAL facility at 15.4 A MeV. The light charged particles produced by the direct reactions were measured using the MUST2 Si-strip telescope array. Above the known 2+ state, two new resonances were observed: at E∗ = 2.6±0.3 MeV (width Γ = 1.6±0.4 MeV) and at 5.3±0.3 MeV with Γ = 2 ± 1 MeV. Through the analysis of the angular distributions, they correspond to a 2+ state and to an L = 1 state, respectively. These new states, challenging the nuclear theories, could be used as benchmarks for checking the microscopic inputs of the newly improved structure models, and should trigger development of models including the treatments of both core excitation and continuum coupling effects

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Background: In view of the increasing recognition of cerebral microbleeds (MCBs) with MRI, there is a need to validate their detection in post-mortem brains in patients with cerebrovascular diseases and dementia. Materials and Methods: Out of 20 post-mortem brains of patients with Alzheimer dementia and with different cerebrovascular lesions, 45 large sections of the cerebral hemispheres, brainstem and cerebellum were submitted to a 7.0-T T₂*-weighted MRI, and afterwards compared to the histological detection of haematomas, MCBs and mini-bleeds (MNBs). Results: The sensitivity, specificity, predictive positive value and predictive negative value of the T₂* imaging to detect MCBs and MNBs were excellent for those in the cortico-subcortical regions. There was a significant overestimation of MNBs in the striatum due to iron deposits unrelated to old haemorrhages. Also in the deep white matter, 42% of MNBs were not detected, while 31% of T₂* hyposignals were not due to MNBs but to vessels filled with post-mortem thrombi. Conclusions: When evaluating the ‘bleeding load’ with 7.0-T T₂*-weighted MRI in post-mortem brain sections of patients with dementia and vascular risk factors, only quantification of small cerebral bleeds in the cortico-subcortical regions is reliable.

The spectroscopy of the unstable 8 He and unbound 7 He nuclei is investigated via the p( 8 He,d) transfer reaction with a 15.7A.MeV 8 He beam from the SPIRAL facility. The emitted deuterons were detected by the telescope array MUST. The results are analyzed within the coupled-channels Born approximation framework, and a spectroscopic factor C 2 S = 4.4±1.3 for neutron pickup to the 7 Heg.s is deduced. This value is consistent with a full p3/2 subshell for 8 He. Tentative evidence for the first excited state of 7 He is found at E* = 0.9±0.5 MeV (width Γ = 1.0 ± 0.9 MeV). The second one is observed at a position compatible with previous measurements, E*=2.9±0.1 MeV. Both are in agreement with previous separate measurements. The reproduction of the first excited state below 1 MeV would be a challenge for the most sophisticated nuclear theories.

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Chronic CML ingestion induced endothelial dysfunction, arterial stiffness and aging in a RAGE-dependent manner.

Proton elastic scattering and inelastic scattering to the first excited state of 6 He have been measured over a wide angular range using a 40.9A MeV 6 He beam. The data have been analyzed with a fully microscopic model of proton-nucleus scattering using 6 He wave functions generated from large space shell model calculations. The inelastic scattering data show a remarkable sensitivity to the halo structure of 6 He. PACS number(s): 25.40.Cm, 25.40.Ep, 24.10.Ht Typeset using REVT E X * present address:INFN-Laboratori Nazionali del Sud,