Furunkel dan Karbunkel merupakan penyakit infeksi kulit yang berupa benjolan berisi nanah yang terjadi pada folikel rambut. Tujuannya adalah sebagai berikut: Untuk menilai efek intervensi (seperti antibiotik topikal, agen antiseptik topikal, antibiotik sistemik, fototerapi, dan sayatan dan drainase) untuk orang dengan folikulitis bakteri dan bisul.
Skabies merupakan penyakit menular yang sangat penting pada populasi dengan tingkat sosial ekonomi rendah di negara berkembang. Skabies atau yang biasa kita dengar dengan nama penyakit kudis tidak mengancam jiwa sehingga biasanya mendapatkan pengobatan yang rendah. Namun sebenarnya skabies yang kronis dan parah dapat menimbulkan komplikasi yang berbahaya. Di Indonesia sendiri penyebaran penyakit skabies banyak terdapat di lingkungan pondok pesantren sebagai akibat dari tingkat pengetahuan yang rendah tentang pola hidup bersih.
Tuberkulosis kulit adalah bentuk tuberkulosis ekstrapulmoner yang jarang, terdiri dari 1-2% kasus. Disebabkan oleh Mycobacterium tuberculosis atau galur terkait, penyakit ini menghadirkan berbagai manifestasi klinis, meniru penyakit kulit kronis lainnya dan menyebabkan diagnosis tertunda. Sebuah kasus skrofuloderma dilaporkan, yang diagnosis dan pengobatannya hanya dibuat enam tahun setelah timbulnya penyakit
Objective: This study aims to determine the survival of prostate cancer (PCa) patients who did not undergo radical prostatectomy, but received hormonal therapy or a combination of radiotherapy and hormonal therapy. Material & Methods: This study was an observational analytic study with a retrospective cohort design, using secondary data to determine baseline data and diagnosis of patients, and using primary data to determine the survival of prostate cancer patients who received combination hormonal and radiotherapy therapy compared with hormonal therapy alone. The analysis was performed using chi-square and contingency coefficients to assess the relationship between survival with factors such as age, stage T, N, M, clinical stage, type of therapy, and prognosis. It also used the Kaplan Maeier curve to assess the survival picture of prostate cancer patients at Sardjito General Hospital. Results: 79 patients met the inclusion criteria. The mean age of the patients was 68 ± 8.4 years. A total of 52 (65.8%) patients received hormonal therapy, and 27 (34.2%) patients received combination hormonal and radiotherapy. There were 41 (51.9%) patients remain life, while 38 (48.1%) of patients died during the monitoring. We found that the Gleason score, PSA level, and clinical stage were significantly associated with patient survival with p <0.005. The 5 years survival rate patient with local, locally advanced clinical stage and PSA level ≤20 ng/ml who received combination hormonal and radiotherapy achieved 100%. Conclusion: Combination of hormonal and radiotherapy was more improving patient survival compared with hormonal therapy only in patient with locally advanced clinical stage, PSA level ≤20 ng/ml and Gleason score ≤7.
Objective: This study aims to determine the effect of diabetes mellitus (DM) and body mass index (BMI) on the risk of prostate cancer and high grade prostate cancer. Materials & method: This study is a retrospective observational study with cross-sectional design, using secondary data to determine the relationship of diabetes mellitus, body mass index and HbA1c levels with the degree of differentiation histopathologic prostate cancer. Data were analyzed using Chi-Square test, T-test and Man Whitney test with a confidence level of p<0.05 and a=0.05. Results: There are 78 samples diagnosed with prostate cancer. A total of 12 (15.4%) samples are diabetes mellitus, 18 (22.9%) samples classified as body mass index more than 23.4 (5.1%) samples have elevated levels of HbA1c levels >6.5. On histopathologic examination, it was found as many as 45 (57.7%) samples with high grade prostate cancer, as much as 9 (11.5%) samples with moderate grade prostate cancer, and as many as 24 (30.8%) samples with low grade prostate cancer. In bivariate analysis diabetes mellitus, BMI>23, and HbA1c level relationship with high grade prostate cancer is not statistically significant with p>0.05. Conclusion: There were no statistically significant relationship between diabetes, BMI and increased levels of HbA1c with high grade prostate cancer.
Indonesia memiliki prevalensi infertilitas sebanyak 2.647.695 dari 238 juta penduduk. Infertilitas dapat disebabkan oleh faktor eksternal seperti obat antibiotik. Gentamisin merupakan antibiotik yang dapat menginduksi stres oksidatif pada saluran reproduksi pria dan menyebabkan kerusakan spermatogenesis. Tomat memiliki banyak kandungan antioksidan salah satunya, likopen yang berpotensi menghentikan kerusakan oksidatif tersebut. Penelitian ini bertujuan untuk mengetahui jumlah dan motilitas sperma yang diinduksi gentamisin. Sampel penelitian ini adalah 30 tikus putih galur Sprague dawley jantan yang dibagi ke dalam 5 kelompok, yaitu kelompok tikus yang tidak diberi perlakuan (K1), diinduksi gentamisin 20 mg/kgbb (K2), diinduksi gentamisin 20 mg/kgbb kemudian diberi jus tomat 25% (P1), 50% (P2), dan 100% (P3). Hasil Uji One Way Anova menunjukkan tidak terdapat pengaruh pemberian jus tomat terhadap jumlah spermatozoa (p>0,05), sedangkan pada motilitas terdapat pengaruh yang signifikan (P=0,00). Hasil uji Post Hoc antar kelompok kontrol dan perlakuan terdapat perbedaan signifikan (p<0,05), sehingga diperoleh kesimpulan bahwa pemberian Jus tomat 50% dan 100% dapat mencegah penurunan motilitas spermatozoa tetapi tidak memiliki efek yang nyata pada jumlah spermatozoa.
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