The first bioinspired microporous metal–organic framework (MOF) synthesized using ellagic acid, a common natural antioxidant and polyphenol building unit, is presented. Bi 2 O(H 2 O) 2 (C 14 H 2 O 8 )· n H 2 O (SU-101) was inspired by bismuth phenolate metallodrugs, and could be synthesized entirely from nonhazardous or edible reagents under ambient aqueous conditions, enabling simple scale-up. Reagent-grade and affordable dietary supplement-grade ellagic acid was sourced from tree bark and pomegranate hulls, respectively. Biocompatibility and colloidal stability were confirmed by in vitro assays. The material exhibits remarkable chemical stability for a bioinspired MOF (pH = 2–14, hydrothermal conditions, heated organic solvents, biological media, SO 2 and H 2 S), attributed to the strongly chelating phenolates. A total H 2 S uptake of 15.95 mmol g –1 was recorded, representing one of the highest H 2 S capacities for a MOF, where polysulfides are formed inside the pores of the material. Phenolic phytochemicals remain largely unexplored as linkers for MOF synthesis, opening new avenues to design stable, eco-friendly, scalable, and low-cost MOFs for diverse applications, including drug delivery.

Metal−organic frameworks (MOFs) are some of the most interesting and promising candidates to sequester toxic H 2 S and SO 2 gases. MOFs show interesting advantages over classic porous materials due to their chemical composition, ligand functionality, cavity dimensions, ease of preparation, and relatively low cost reactivation. The optimization of the physical−chemical interactions between MOFs and H 2 S and SO 2 molecules is the key to further amplification of their capture. Reversibility after the adsorption of H 2 S and SO 2 can be modulated through noncovalent bonding between functionalized ligands (within MOF structures) and H 2 S and SO 2 . This review aims to summarize recent advances in the development of MOF-based systems for the capture and removal of H 2 S and SO 2 . We anticipate that this review article can offer very useful information on the significant and rapid progress of the enhancement of H 2 S and SO 2 capture by MOFs.

MIL-101(Cr)-4F(1%) shows a high uptake and high chemical stability to dry and humid SO2 and a remarkable cyclability. In situ DRIF spectroscopy upon the adsorption of CO identified the preferential adsorption sites for this MOF material.

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