Introduction:The coronavirus 2019 pandemic has become a serious threat to the global health and spreading rapidly. Dialysis patients may have developed anxiety because of their disease characteristics during this pandemic. The aim of this study was to assess the reliability and quality of the most viewed English-language YouTube videos on COVID-19 and dialysis link.Methods: A YouTube search was achieved using the key words "COVID-19 dialysis," "SARS CoV-2 dialysis," "coronavirus hemodialysis," and "COVID peritoneal dialysis." Results: Among the 43 videos analyzed, 24 (55.8%) were high quality, 11 (25.6%) were moderate quality, and 8 (18.6%) were of low quality according to global quality score. Significant differences were found between the groups in modified DISCERN scores and the number of views, likes, comments. Conclusion:The most reliable sources such as universities, governments, professional societies should better use YouTube for dissemination of accurate, reliable, and useful health-related information to the general public.
Objective: Urinary tract infections (UTIs) are one of the most common infections in children. The aim of this study was to assess and compare the etiology and antibiotic susceptibility results of urine cultures obtained between 2013-2015 and 2019-2021 and evaluate local epidemiologic differences over years. Materials and Methods: A total of 1,000 samples with positive urine cultures (500 cultures each for the 2013-2015 and 2019-2021 periods) and antibiogram results were included in this study. Results: The most grown uropathogens were Escherichia coli and Klebsiella spp. in both two periods. E. coli and Klebsiella spp. showed high resistance to ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, cefuroxime, and ceftriaxone. The resistance rates of E. coli to ampicillin, amoxicillin and trimethoprim-sulfamethoxazole were reported as 65%, 46%, and 45%, respectively and significantly increased in 2019-2021 compared to 2013-2015 (p
Background Familial Mediterranean fever (FMF) is the most seen monogenic periodic fever syndrome characterised by bouts of fever and serositis. It is known that subclinical inflammation (SI) can persist in the symptom-free period and lead to amyloidosis even under colchicine treatment. This study aimed to evaluate the role of the fibrinogen-to-albumin ratio (FAR) in FMF and its correlation with SI. Material and Methods A total of 112 patients with FMF and 78 controls were enrolled in this retrospective study. Demographic, laboratory and genetic data were obtained from the hospital records. Results The FAR values of the FMF cases were significantly higher than the control group (p<0.001). In the FMF group, the patients with SI had higher FAR values than those without SI (p<0.001). FAR was positively correlated with SI (r=0.413, p<0.001). The receiver operating characteristic curve analysis showed that FAR had a higher area under the curve value than albumin and fibrinogen. Conclusion Detecting SI in patients with FMF is crucial in preventing amyloidosis, the most devastating complication of FMF. FAR is a simple, inexpensive, easily obtained indicator which can be used for reflecting SI in FMF.
Öz Ailesel Akdeniz Ateşi (AAA) tekrarlayan ateş ve ateşe eşlik eden seröz zarların inflamasyonu ile karakterli otozomal resesif geçiş gösteren otoinflamatuar hastalıktır. Özellikle Yahudiler, Araplar, Türkler ve Ermeniler'de sık olarak görülür. Kendi kendini sınırlayan ateş, karın ağrısı, göğüs ağrısı, eklem ağrısı ve şişliği, erizipel benzeri eritem atakları en sık belirti ve bulgulardır. Henoch Schönlein Purpura ve Poliarteritis Nodosa ile AAA birlikteliği sıktır. Tanı koymak amacı ile kullanılan spesifik bir test olmayıp hastalığın tanısı klinik olarak konulur. Atak sırasında bakılan akut faz reaktanlarında artış ve atak dışı dönemde bunların normale dönmesi tanıyı destekler. AAA ayırıcı tanısında, başta diğer periyodik ateş sendromları olmakla birlikte romatolojik hastalıklar, enfeksiyonlar, akut batın sendromları, maligniteler, porfiria gibi genetik hastalıklar göz önünde bulundurulmalıdır. 1972 yılından beri hastalığın tedavisinde etkin ilaç olarak kolşisin kullanılmaktadır. Kronik inflamasyona sekonder olarak gelişen AA (sekonder) amiloidoz, AAA'nın en ciddi komplikasyonudur. Kolşisin tedavisi atakların süre, sıklık ve şiddetini azalttığı gibi amiloidoz riskini de önler. Son yıllarda kolşisin tedavisini tolere edemeyen veya ilaca yanıt alınamayan hastalarda interlökin-1 antagonistlerinin kullanımı ile başarılı sonuçlar elde edilmiştir.
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