AbstrakLatar belakang: Scaffold (biomaterial) adalah rangka yang digunakan dalam transplantasi sel punca mesenkimal. Sebelum digunakan perlu dilakukan uji biokompatibilitas secara in vitro melalui pengujian toksisitas langsung dan tak langsung MTT assay [3-(4,5-dimethylthiazol-2-yl
AbstractBackground: Scaffold (biomaterial) biocompatibility test should be performed in vitro prior to in vivo stem cell application in animal or clinical trial. These test consists of direct and indirect toxicity test (MTT assay [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide]). Those tests were used to identify cell morphological changes, cell-substrate adhesion impairment, and reduction in cell proliferation activity.
There was no association between type of surgery and tumour recurrence, metastasis, or outcome. Curettage with adjuvant therapy was more commonly performed for stage 1 and 2 tumours, whereas wide resection was more for stage 3 tumours. Metastasis was associated with stage 3 tumour and mortality but not recurrence.
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