AbstrakPada penelitian ini dilakukan formulasi, karakterisasi dan stabilitas fisik sediaan mikroemulsi tipe air dalam minyak. Minyak yang digunakan sebagai fase minyak dalam pembuatan mikroemulsi adalah VCO, minyak kelapa sawit , minyak zaitun dan minyak kedelai , fase air aquademineralisata, Span® 80 dan Tween® 80 sebagai surfaktan dan propanol sebagai kosurfaktan. Setiap formula dilakukan 3 replikasi dan ditentukan karakteristik fisik yang meliputi pengamatan organoleptis, pengukuran berat jenis, pengukuran droplet, pengukuran viskositas dan sifat alir, dan pengukuran pH. Penentuan karakteristik fisik dilakukan pada saat awal terbentuk mikroemulsi dan setelah penyimpanan selama 5 minggu dalam suhu kamar. Selain itu, juga dilakukan uji stabilitas fisik yang meliputi uji sentrifugasi dengan kecepatan 10.000 rpm selama 30 menit, uji freeze-thaw selama 6 siklus, dan uji heating stability dengan oven suhu 60ºC, 70ºC, 80ºC, 90ºC, dan 100ºC selama 5 jam. Dari data yang didapatkan dilakukan analisis statistik menggunakan metode t-Test dan one way ANOVA. Dari penentuan karakteristik dan stabilitas fisik yang telah dilakukan didapatkan hasil bahwa mikroemulsi dengan minyak VCO, minyak kelapa sawit dan minyak kedelai memiliki karakteristik dan stabilitas fisik yang lebih baik dibandingkan dengan mikroemulsi dengan minyak zaitun. AbstractThis research consists of formulation, characterization and physical stability of the microemulsion of water-in-oil type. On the microemulsion, VCO, palm oil, olive oil and soybean oil were used as oil phase, aqua demineralisata used as the aqueous phase, a combination of Span® 80 and Tween® 80 as a surfactant and propanol as cosurfactant. Each formula was three times replication done and determined the physical characteristics including organoleptic observations, measurements of density, droplet, viscosity, flow properties, and pH. Determination of physical characteristics was done at the beginning of the microemulsion formed and after 5 weeks storage at room temperature. The physical stability test including the centrifugation test at 10,000 rpm for 30 minutes, the freeze-thaw test for 6 cycles, and heating stability with the oven temperature of 60ºC, 70ºC, 80ºC, 90ºC and 100ºC for 5 hours were done. The data obtained were analyzed using t-Test and oneway ANOVA. Based on the characteristic and physical stability tests, it was showed that microemulsion with VCO, palm oil and soybean oil had better physical characteristics and stability compared to the microemulsion with olive oil.
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