Objective: Inflammation is one of the most common complications observed when using orthodontic miniscrews. Chlorhexidine mouthwash can beused to prevent and reduce the degree of inflammation, but long-term use of this solution may lead to some side effects. This study sought to evaluatethe peri-miniscrew antibacterial effect of 1% chitosan, a biomaterial with antibacterial properties, relative to 0.2% chlorhexidine mouthwash.Methods: A randomized, double-blind clinical trial was conducted at the Dental Teaching Hospital and Oral Biology Research Laboratory at theUniversity of Indonesia from February to June 2019. Thirty subjects (25 females and five males) were randomly assigned to rinse with 1% chitosan(n=10), 0.2% chlorhexidine digluconate (n=10), and Aquadest (n=10) in addition to their usual oral hygiene procedure for 4 days. Peri-miniscrewclinical inflammation signs were recorded and peri-miniscrew plaque collected before and after 4 days of rinsing. The total bacterial and red-complexbacteria count in plaque samples were evaluated by a real-time polymerase chain reaction.Results: Chitosan and chlorhexidine showed antibacterial activity, reducing total bacterial count around orthodontic miniscrews (p<0.05). Theantibacterial activity of chitosan on total bacteria was not significantly different from that of chlorhexidine (p≥0.05). Regarding the antibacterialactivity of chitosan on red-complex bacteria, the best result seen was a 58% bacteria count reduction in Tannerella denticola.Conclusion: Chitosan has potential antibacterial activity and could be used in mouthwash to maintain peri-miniscrew hygiene.

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ABSTRAKPendahuluan: Gigi yang protusif dan berjejal parah sangat mempengaruhi estetika wajah seseorang, oleh karena itu kondisi ini perlu diatasi secara ortodonti karena dapat mempengaruhi kepercayaan diri dan kualitas hidup seseorang terutama wanita. Selain kebutuhan ruang, perawatan ortodonti yang dilakukan haruslah juga memperhatikan kontrol penjangkaran yang optimal. Tujuan laporan kasus ini menyampaikan penatalaksanaan perawatan ortodonti maloklusi kelas I dengan overjet besar Laporan kasus: Seorang pasien wanita usia 25 tahun datang ke Klinik Spesialis Ortodonti RSKGM FKG UI untuk mendapatkan perawatan ortodonti karena kondisi giginya yang sangat protusif. Secara klinis diketahui bahwa pasien memiliki maloklusi kelas I dengan overjet 10 mm. Perawatan ortodonti dilakukan menggunakan breket preadjusted sistem MBT slot.022 serta penjangkaran NHA. Simpulan: Hasil perawatan menunjukkan senyum pasien yang lebih estetik dengan inklinasi gigi anterior dan overjet yang terkoreksi dengan baik. NHA bermanfaat sebagai penambah penjangkaran pada kasus overjet besar yang membutuhkan penjangkaran maksimum, sehingga dapat dijadikan alternatif pilihan alat penambah penjangkaran dalam perawatan ortodonti cekat.