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Antimicrobial resistance is recognized as one of the most important global human health problems in the 21st century. The balance between clinical need and resistance prevention is further compromised by agricultural antibiotic use as some countries have actively used colistin in animal production. Antimicrobial-resistant microorganisms have been found in humans, food, animals, plants, and the environment (water, soil, and air), and they can move between ecosystems. The problem of antimicrobial resistance is currently seen in the concept: One Health. This approach encourages interdisciplinary collaborative efforts that work locally. The beginnings of the mcr gene's presence in America dates to 2012 and the first report of disseminating the mcr-1 gene was described for Kelp gulls (Larus dominicanus) from Ushuaia, Argentina. It can be associated with the possible dissemination of the gene in the American continent through migratory birds. The mcr-1 gene is disseminated in countries, such as Argentina,

Considering the broad potential of the genus Cymbopogon, here we present a systematic literature survey on it’s antimicrobial potential. This is a review, articles from the Scielo and PubMed platforms. The articles surveyed were published between 2015 and 2020, with the theme of microbiology, including ethnobotanical studies, literature reviews, in vitro, in vivo, reports of clinical trials. Works outside the selected period, duplicate articles, and those only reporting infections of plants by the microorganism were excluded. 98 studies were selected, 74% found in PubMed and 26% in Scielo. Of this total, 21% were ethnobotanical/ethnopharmacology or literature reviews, most of them reporting the use of infusions of the species C. citratus (DC.) Stapf. Moreover, in 57% of the studies, survey respondents did not report antimicrobial use. In relation to 79% of the experimental studies, it was observed that 77% reported total inhibition of microbial growth, 3% indicated moderate growth inhibition, 4% low growth inhibition and 5% reported no inhibition. Among the microbial species analyzed were Escherichia coli, Pseudomonas aeruginosa, Borrelia burgdorferi, Candida albicans, Salmonella enterica and Saccharomyces cerevisiae. In addition, 5% of the articles reported antiviral activity, 5% parasitic control, 1% preventive action against contamination by mesophilic microorganisms. Although the population is not aware of the antimicrobial activity of Cymbopogon sp., studies have demonstrated its antimicrobial potential, thus the extracts of this genus can be an alternative for use in folk medicine as well as a source of new drugs with antimicrobial action.