No abstract

To investigate climatic, spatial, temporal, and environmental patterns associated with hantavirus pulmonary syndrome (HPS) cases in the Four Corners region, we collected exposure site data for HPS cases that occurred in 1993 to 1995. Cases clustered seasonally and temporally by biome type and geographic location, and exposure sites were most often found in pinyon-juniper woodlands, grasslands, and Great Basin desert scrub lands, at elevations of 1,800 m to 2,500 m. Environmental factors (e.g., the dramatic increase in precipitation associated with the 1992 to 1993 El Niño) may indirectly increase the risk for Sin Nombre virus exposure and therefore may be of value in designing disease prevention campaigns.

5Whole genome sequencing (WGS) of bacteria is becoming standard practice is much more flexible in terms of data input types, job management systems, 2 5 diversity of supported tools, and output formats. We also demonstrate differences in results based on the choice of the reference genome and choice of inferring method and can be obtained from tgennorth.github.io/NASP.