This is the first study to examine the involvement of ROCK1 and ROCK2 gene variations in the risk of POAG development. This study demonstrated that the polymorphisms studied are not associated with the increased risk of development of POAG in the Turkish population.

The study has found that in the treatment of SEI, which developed after EKC, statistically similar results can be obtained with loteprednol, which is known to have fewer adverse effects.

ÖzetÇalışmamızda pterjium cerrahisinde uygulanan farklı cerrahi teknikler arasında nüks oranlarının araştırılması amaçlandı. Çalışmaya ameliyat sonrası en az 6 ay takibi bulunan, 128 hastanın 130 gözü alındı. Hastalara cerrahi yöntem olarak çıplak sklera bırakılması, intraoperatif MMC (Mitomisin C) uygulaması, geniş tenon eksizyonu ve konjonktival otogreft uygulaması yöntemleri uygulandı. Hastaların yaşı, cinsiyeti, takip süreleri, uygulanan cerrahi prosedür, nüks gelişme zamanları ve komplikasyonlar not edildi. Sonrasında hesaplanan nüks oranları istatistiksel olarak analiz edildi. Ortalama 9,42±3,93 ay takip edilen hastaların %25,4'ünde nüks saptandı. En yüksek nüks oranı %55,2 ile çıplak sklera tekniğinde tespit edildi. Konjonktival otogreft uygulamasında %14,6, intraoperatif MMC uygulamasında %13,5, geniş tenon eksizyonunda %31,3 oranında nüks görüldü. Çıplak sklera bırakılması ile konjonktival otogreft uygulaması ve intraoperatif MMC uygulaması arasında nüks açısından anlamlı fark saptanırken, geniş tenon eksizyonu ile diğer 3 yöntem arasında nüks bakımından farklılık saptanmadı. Çıplak sklera bırakılması diğer yöntemlerden yüksek nüks oranlarına sahiptir. Birbirine yakın düşük nüks oranları mevcut olsa da potansiyel komplikasyonlar göz önüne alındığında konjonktival otogreft yöntemi, intraoperatif MMC uygulamasına tercih edilmelidir. Geniş tenon eksizyonunun diğer yöntemlerle kıyaslanması için geniş vaka grupları ile yapılacak çalışmalara ihtiyaç vardır. Anahtar kelimeler: Mitomisin C; nüks; pterjium AbstractThis study was done to compare the rates of recurrence of pterygium following performed different surgical techniques for treatment. One hundred and thirty eyes of 128 patients were examined following the surgical treatment in our clinic between February 2004-January 2008 with mean follow-up of six months. We performed bare sclera, application of intraoperative MMC (Mitomycin C), wide tenon's membrane excision and conjunctival auto-grafting techniques. The age and sex of the patients and follow-up duration, operation techniques, complications and the recurrence times were noted. Median follow-up was 9,42±3,93 months and the recurrence rate was %25,4. The highest recurrence rate was %55,2 (in the bare sclera technique), the lowest recurrence rate was %13,5 (in the intraoperative MMC technique). It was %14,6 in conjunctival auto-grafting technique group and %31,3 in the complete tenon's membrane excision group. Statistically, the rate of recurrence was meaningful between the bare sclera group and the conjunctival autografting group and between intraoperative MMC group. But the outcomes of the wide tenon's membrane excision group and the other three groups weren't meaningful. Bare sclera technique had the highest recurrence rates. Though, there wasn't meaningful recurrence rates between intraoperative MMC technique and the conjunctival auto-grafting technique, we must prefer the second one because of its lowest complication risks. The wide tenon's membrane excision technique needs some more studies to com...

ÖzetBu çalışmada eksternal dakriyosistorinostomi ameliyatları esnasında yapılan tek ve çift fleb anastomoz sonuçlarının karşılaştırılması amaçlanmıştır. Kliniğimizde Aralık 2009-Haziran 2012 tarihleri arasında kronik dakriyosistit nedeniyle eksternal dakriosistorinostomi ameliyatı uygulanan 168 olgunun, 168 gözü retrospektif olarak değerlendirildi. Tüm olgulara flepler hazırlandıktan sonra silikon tüp entübasyonu yapıldı. Tüm olgular yaş, cinsiyet, cerrahi sırasında gelişen komplikasyonlar ve cerrahinin başarısı yönünden değerlendirildi. Lakrimal irrigasyonda nazal geçişin olması ve epifora şikayetinin düzelmesi cerrahi başarı olarak kabul edildi. AbstractThe aim of this study was to compare the success rate of single and double flaps anastomosis technique in the course of external dacriyocystorhinostomy (DCR) operation. Between December 2009 and June 2012, 168 patients operated for chronic dacryocystocystit by external DCR. All of these patients lacrimal canals were entubated with slicone tube after flaps were prepared . Patients were classified by their age, gender, complication and success rate of the surgery. Free nasal passage in lacrimal irrigation and relief from complaints of epiphora were determined as surgical success criteria. Of 168 patients who take part in the study, 97 were female, 71 was male. 86 of these patients operated by single flap technique, 82 of them operated double flaps anastomosis technique by external DCR. Out of 82 patients who operated double flap anastomosis, 31 of them were male and 51 were female. Median was 45.6 ±18.4. Out of 86 patients operated by single flap technique 40 of them were male and 46 of them were female median was 43.5 ±20.6. Median follow up time of double flap group was 20.4 ±4.3 months, single flap group was 19 ±9.7 months. Surgical success rate of double flap group was 95.2%, and 95.4% on the single flap group. The success rates were not found to be statistically different between two groups of patients (p>0,05). Our study suggests that external DCR with double flaps anastomosis has no difference from external DCR with single flap in terms of the surgical success rates. Single flap technique is much easier to perform and preferable.

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Purpose: This study aimed to evaluate the effect of excision of the narrow orbicularis oculi strip in cosmetic upper eyelid blepharoplasty on eyebrow position and balance of muscles determining eyebrow position in favor of elevation. Methods: Present study evaluated the influence of skin and 3 mm orbicularis strip resection during cosmetic upper blepharoplasty on eyebrow position. This Retrospective study included a review of patients undergoing cosmetic upper blepharoplasty that skin and orbicularis strip were resected between September 2020 and March 2022. Patients with visual field complaints, a prior history of upper or lower lid blepharoplasty, browpexy surgery, or ptosis repair were excluded. Digital photographs were analyzed using NIH ImageJ software to measure preoperative and postoperative eyebrow height as the vertical distance from the center of the pupil to the lowest eyebrow hair. All patients were monitored for nine months after the surgical procedure. During the follow-up period, it was ensured that minimally invasive or invasive intervention was not made that can change eyebrow position. Results: According to the results, no significant change was observed in eyebrow height after the surgical procedure in patients who have undergone 3 mm orbicular strip excision during upper eyelid blepharoplasty surgery. The mean eyebrow height was 17.78 mm prior to surgery and 17.67mm after surgery. The mean change was -0.11 mm, which was not statistically significant. (p=0.24) Conclusion: The present study implies that 3 mm orbicularis muscle resection did not cause any change in eyebrow position and suggests that orbicular resection may not cause any loss of function in the eyebrow depressor muscles.

The aim of this study was to compare the effectiveness of intralesional triamcinolone acetonide injection with incision and curettage for the treatment of chalazion. Forty-six patients who were treated with conservative measures for at least 1 month without any healing were included into the study. Twenty-seven of them were treated with intralesional triamcinolone acetonide injection and 19 of them with incision and curettage via conjunctival approach. Regression of chalazion was observed in 24 (88%) of 27 patients who were injected intralesional triamcinolone acetonide, and 18 (95%) of 19 patients who were applied incision and curettage. No statistical difference was seen between the success rate of these two treatment options. There was not any complication in patients who were treated with incision and curettage but local depigmentation was seen in one patient (3.7%) who was treated with triamcinolone acetonide at the second month at follow-up. This depigmentation spontaneously disappeared at the 4th month. As a result in terms of success and complication ratios, effectiveness and reliability of these two methods were found similar in the treatment of chalazion. ÖzetBu çalışmada şalazyonlu olguların tedavisinde uygulanan, lezyon içi triamsinolon asetonid enjeksiyonu ile insizyon ve küretaj şeklinde uygulanan cerrahinin etkinliğinin karşılaştırılması amaçlandı. Çalışmada en az 1 ay konservatif yöntemlerle tedavi edilmiş ancak lezyon boyutlarında gerileme izlenmeyen toplam 46 olgunun 27'sine şalazyon içi triamsinolon asetonid enjeksiyonu, 19'una konjonktival yaklaşımla insizyon ve küretaj cerrahisi uygulandı. Triamsinolon asetonid enjeksiyonu uygulanan 27 olgunun 24'ünde (%88), insizyon ve küretaj uygulanan 19 olgunun 18'inde (%95) şalazyonun gerilediği gözlendi. Tedavi yöntemlerinin başarı oranları arasında istatistiksel olarak anlamlı fark gözlenmedi (p=0.67). İnsizyon ve küretaj uygulanan olgularda herhangi bir komplikasyon izlenmezken, triamsinolon asetonid uygulanan 1 (%3.7) olguda takipte 2. ayda lokal depigmentasyon görüldü. Bu depigmentasyon 4. ayda kendiliğinden kayboldu. Sonuç olarak her iki yöntemin şalazyon tedavisindeki başarı oranları ve komplikasyon izlenmemesi göz önüne alındığında etkinlik ve güvenirlikleri birbirine yakın bulundu. Anahtar kelimeler: Şalazyon; insizyon ve küretaj; triamsinolon asetonid Correspondence: Ferhat Zorlu,