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Revised in adolescents with major depressive disorderThis research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors for the conduct of the research and/or preparation of the article. This article has been published in Stallwood et al. (2021). Systematic review: The measurement properties of the Children's Depression Rating Scale-Revised in adolescents with major depressive disorder.

CONTEXT: Recently a standard set for overall pediatric health outcomes in routine care was developed, which includes patient (or proxy) reported outcome measures (PROMs) for global health, cognitive functioning, and self-efficacy. OBJECTIVES: To determine whether the following PROMs have sufficient measurement properties to be used in pediatric routine care: PROMIS Pediatric and Parent Proxy Scale - Global Health 7+2, PROMIS Parent Proxy Short Form - Cognitive Function 7a, and NIH Toolbox Self-Efficacy CAT Ages 13 to 17. DATA SOURCES: Embase, Psych INFO, and Web of Science were searched from year of inception of each PROM to May 25, 2020; Medline to October 24, 2022. STUDY SELECTION: English, full-text peer-reviewed articles that evaluated measurement properties of included PROMs were eligible. DATA EXTRACTION: The COSMIN guideline for systematic reviews was used to appraise eligible studies and synthesize the overall evidence. RESULTS: Screening >4000 titles yielded 4 to 6 eligible empirical studies for each PROM. The PROMIS instruments had sufficient content validity with low-quality evidence and at least low-quality evidence for sufficient structural validity and internal consistency. The NIH Toolbox lacked essential evidence for content validity. LIMITATIONS: Assessments of measurement properties were based on information reported in the included studies; underreporting might have led to less favorable ratings. CONCLUSIONS: The PROMIS instruments assessed in this review measure their intended construct for their targeted age group; clinicians can use these PROMs in pediatric routine care. Additional studies evaluating measurement properties, including content validity, are needed for the NIH Toolbox before it should be recommended for use in clinical practice.

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The objectives of this review are to determine if the ADRS and the QIDS have sufficient measurement properties according to the COSMIN guidelines, to evaluate the quality of this evidence, and to determine whether these OMIs meet at least minimum COSMIN criteria to support their use in youth with MDD and consideration for inclusion in a COS for this population (i.e., sufficient content validity (any level) AND at least low quality evidence for sufficient internal consistency).

The Children’s Depression Rating Scale-Revised (CDRS-R) is the most commonly used method to measure depression in treatment studies of teens with depression, but itis unknown whether the CDRS-R is appropriate for the purpose of measuring depression inadolescents. This study aimed to identify all existing evidence of the key measurement propertiesof the CDRS-R (for example, how well the scale measures what it is supposed to measure) in teens with depression, and to evaluate these properties using a well-establishedmethod developed by the COSMIN Initiative (https://www.cosmin.nl/). The study concludes thatit is unclear whether the CDRS-R can appropriately measure depression symptom severity in treatment studies of teens with depression based on current available evidence. It is important that the best methods are used to measure outcomes to ensure that results from clinical researchstudies in teens with depression are meaningful and useful to relevant stakeholders, including patients, caregivers, health care providers, researchers, and policymakers.

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