No abstract

A systematic review was conducted in compliance with PRISMA statement standards to identify all studies reporting outcomes of laparoscopic resection of benign or malignant lesions located in caudate lobe of liver. Pooled outcome data were calculated using random-effects models. A total of 196 patients from 12 studies were included. Mean operative time, volume of intraoperative blood loss, and length of hospital stay were 225 minutes (95% confidence interval [CI], 181-269 minutes), 134 mL (95% CI, 85-184 mL), and 7 days (95% CI, 5-9 days), respectively. The pooled risk of need for intraoperative transfusion was 2% (95% CI, 0%-5%). It was 3% (95% CI, 1%-6%) for conversion to open surgery, 6% (95% CI, 0%-19%) for need for intra-abdominal drain, 1% (95% CI, 0%-3%) for postoperative mortality, 2% (95% CI, 0%-4%) for biliary leakage, 2% (95% CI, 0%-4%) for intra-abdominal abscess, 1% (95% CI, 0%-4%) for biliary stenosis, 1% (95% CI, 0%-3%) for postoperative bleeding, 1% (95% CI, 0%-4%) for pancreatic fistula, 2% (95% CI, 1%-5%) for pulmonary complications, 1% (95% CI, 0%-4%) for paralytic ileus, and 1% (95% CI, 0%-4%) for need for reoperation. Although the available evidence is limited, the findings of the current study might be utilized for hypothesis synthesis in future studies. They can be used to inform surgeons and patients about estimated risks of perioperative complications until a higher level of evidence is available.

Aims to evaluate the procedural outcomes of laparoscopic caudate lobe resection. Methods We performed a systematic review in accordance with PRISMA statement standards to identify all studies reporting the outcomes of laparoscopic resection of caudate lobe of liver. The population of interest included adult patients with benign or malignant lesions located in caudate lobe of liver. The intervention of interest included laparoscopic resection of caudate lobe of liver. Random-effects models were applied to calculate pooled outcome data. Results 196 patients from 12 studies were included. The mean operative time, volume of intraoperative blood loss, and length of hospital stay were 225 mins (181–269), 134 ml (85–184), and 7 days (5–9), respectively. The pooled risks of need for intraoperative transfusion was 2% (0–5%), conversion to open surgery was 3% (1–6%), need for intra-abdominal drain was 6% (0–19%), postoperative mortality was 1% (0–3%), biliary leakage was 2% (0–4%), intra-abdominal abscess was 2% (0–4%), biliary stenosis was 1% (0–4%), postoperative bleeding was 1% (0–3%), pancreatic fistula was 1% (0–4%), pulmonary complications was 2% (1–5%), paralytic ileus was 1% (0–4%), and need for reoperation was 1% (0–4%). Conclusions Evidence from case series suggests that laparoscopic approach may be safe, feasible and promising for resection of lesions located in caudate lobe of liver. The findings of current study can be used for hypothesis synthesis in future studies and can be used to inform surgeons and patients about the estimated risks of perioperative complications until a higher level of evidence is available.