therapy for outpatients with eating disorders: Effectiveness for a transdiagnostic group in a routine clinical setting. Behaviour Research and Therapy,[68][69][70][71][72][73][74][75] https://doi.org/10.1016/j.brat.2015.03.001 eprints@whiterose.ac.uk https://eprints.whiterose.ac.uk/ Reuse Unless indicated otherwise, fulltext items are protected by copyright with all rights reserved. The copyright exception in section 29 of the Copyright, Designs and Patents Act 1988 allows the making of a single copy solely for the purpose of non-commercial research or private study within the limits of fair dealing. The publisher or other rights-holder may allow further reproduction and re-use of this version -refer to the White Rose Research Online record for this item. Where records identify the publisher as the copyright holder, users can verify any specific terms of use on the publisher's website. TakedownIf you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing eprints@whiterose.ac.uk including the URL of the record and the reason for the withdrawal request. These preliminary studies of effectiveness indicate that CBT can be delivered with strong outcomes in routine clinical settings. However, it is well-established that clinicians routinely fail to use CBT when working with the eating disorders (e.g., Tobin, Banker, Weisberg, & Bowers, 2007) or that they deliver it in sub-optimal ways (Waller, Stringer, & Meyer, 2012), expressing concerns about the use of those core CBT techniques (e.g., Turner, Tatham, Lant, Mountford, Waller, 2014) and discounting the use of evidence-based manuals to support their work (e.g., Waller et al., 2013). Therefore, there is a need for further evidence from other routine clinical settings to demonstrate that CBT for the eating disorders is an effective treatment, which others can use in their own clinics. This study aims to build on previous work by testing the effectiveness of CBT in a further routine clinical setting. It reports clinical outcomes for a large group of transdiagnostic patients who were offered CBT in a community eating disorders service in the UK. Unlike previous studies, there were very few exclusion criteria and no BMI cut-off. In this case, the variant of CBT used was based on a combination of elements from the relatively similar approaches of Fairburn (2008) and Waller et al. (2007), as used by Byrne et al. (2011) and Waller et al. (2014) respectively.

Acute kidney injury (AKI) is a common reason for hospital admission and complication of many inpatient procedures. The temporal incidence of AKI and the association of AKI admissions with in-hospital mortality are a growing problem in the world today. In this review, we discuss the epidemiology of AKI and its association with in-hospital mortality in the United States. AKI has been growing at a rate of 14% per year since 2001. However, the in-hospital mortality associated with AKI has been on the decline starting with 21.9% in 2001 to 9.1 in 2011, even though the number of AKI-related in-hospital deaths increased almost twofold from 147,943 to 285,768 deaths. We discuss the importance of the 71% reduction in AKI-related mortality among hospitalized patients in the United States and draw on the discussion of whether or not this is a phenomenon of hospital billing (coding) or improvements to the management of AKI.

Background--Acute kidney injury (AKI) and dialysis-requiring AKI (AKI-D) are common, serious complications of cardiac procedures.

Background Acute kidney injury (AKI) is a common complication following cardiac surgery. While AKI severity is associated with increased risk of short-term outcomes, its long-term impact is less well understood. Methods Adult patients undergoing isolated coronary artery bypass graft surgery at eight centers were enrolled into the Northern New England biomarker registry (n=1,610). Patients were excluded if they had renal failure (n=15) or died during index admission (n =38). AKI severity was defined using the AKI Network (AKIN). We linked our cohort to national Medicare and state all-payer claims to ascertain readmissions and to the National Death Index to ascertain survival. Kaplan-Meier and multivariate Cox’s proportional hazard modeling were conducted for time to readmission and death over 5 years. Results Within 5 years, 513 patients (33.8%) developed AKI with AKIN stage 1 (29.9%) and stage 2–3 (3.9%). There were 620 (39.9%) readmissions and 370 (23.8%) deaths. After adjustment, Stage 1 AKI patients had a 31% increased risk of readmission (95%CI: 1.10–1.57), while Stage 2–3 patients had a 98% increased risk (1.41–2.78) compared to those with no AKI. Relative to those without AKI, Stage 1 patients had a 56% increased risk of mortality (1.14–2.13) while those Stage 2–3 patients had a 3.5-times higher risk (2.16–5.60). Conclusions AKI severity using the AKIN stage criteria is associated with a significantly increased risk of 5-year readmission and mortality. Our findings suggest efforts to reduce AKI in the perioperative period may have significant long-term impact for patients and payers in reducing mortality and healthcare utilization.

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