The purpose of the presented investigations is to design, construct and establish the characteristic performance of the Jagiellonian Positron Emission Mammography(J-PEM), being designed for the detection and diagnosis of breast cancer. Its construction is based on a novel idea of PET tomography based on plastic scintillators and wavelength shifter (WLS) and a new concept of positronium imaging. We have prepared a simulation program based on Monte Carlo methods for optimizing the geometry and material of the J-PEM prototype. Here we present the first results from the simulations and a brief review of the state of art of breast imaging modalities and their characteristics motivating our investigation.
The aim of the study is the presentation of an unexpectably long, eight year survival of a female patient, suffering from glioblastoma multiforme (GBM), who completed radical treatment, which was composed of neurosurgery followed by radiochemotherapy with temozolomide. The condition of the patient was regularly examined and brain computed tomography was performed to exclude recurrence of the disease. During eight years of follow-up, no relapse was observed. After radical treatment, the neurological condition of the patient systematically improved. At present, as a result of rehabilitation, neurological symptoms are not observed. Currently, the patient does not require any drugs, including anticonvulsants. In conclusion, despite extremely unfavorable prognosis, every patient who is fit enough should receive radiochemotherapy with temozolomide after neurosurgery, because longterm survival in GBM is achievable. In case of technical difficulties (unavailable radiotherapy or chemotherapy in smaller hospitals) patients should be referred to oncology centers for combined treatment.
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