Eight-year follow-up of a patient with glioblastoma multiforme who completed radical treatment

Abstract

The aim of the study is the presentation of an unexpectably long, eight year survival of a female patient, suffering from glioblastoma multiforme (GBM), who completed radical treatment, which was composed of neurosurgery followed by radiochemotherapy with temozolomide. The condition of the patient was regularly examined and brain computed tomography was performed to exclude recurrence of the disease. During eight years of follow-up, no relapse was observed. After radical treatment, the neurological condition of the patient systematically improved. At present, as a result of rehabilitation, neurological symptoms are not observed. Currently, the patient does not require any drugs, including anticonvulsants. In conclusion, despite extremely unfavorable prognosis, every patient who is fit enough should receive radiochemotherapy with temozolomide after neurosurgery, because longterm survival in GBM is achievable. In case of technical difficulties (unavailable radiotherapy or chemotherapy in smaller hospitals) patients should be referred to oncology centers for combined treatment.