Chikungunya virus (CHIKV) causes a self-limiting disease characterized by the
onset of fever, skin rash and persistent arthralgia. In the last decade, it has
emerged as a serious public health problem causing several outbreaks around the
world. Here, we report the CHIKV genotype characterization during the 2016 CHIKV
outbreak in Alagoas State, Brazil. Partial E1 sequence from CHIKV-positive
samples coming from different cities of Alagoas were submitted to DNA sequencing
followed by phylogenetic analysis thus characterizing the virus genotype. The
circulating CHIKV virus in Alagoas during 2016 outbreak belongs to the
East-Central South African genotype. In this way, virus genotyping to monitoring
the spread of CHIKV is needed to continued surveillance supporting the
development of prevention strategies, mainly in endemic areas of mosquitoes and
arboviruses co-circulation.
The aim of this study was to present the circulating HPV genotypes in a population from northeast Brazil. HPV was detected by nested-Polymerase Chain Reaction (nPCR) method using primers MY09/11 and GP5+/6+. HPV sequencing was performed by the method of Sanger. The HPV 16 was the most frequent (35.7%), followed by HPV 58 (14.3%). In conclusion, we identified, in one population from Northeast Brazil, a low prevalence of HPV 18 present in the vaccine provided by Unified Health System and a high prevalence of HPV 58 which is not present in this vaccine.
KEYWORDS: HPV, Oncology and Woman Healthy.
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