Background and Objective: Diseases caused by microbes vectored by mosquitoes are still a health problem in tropical countries today.DHF and Malaria are the two primary diseases vectored by mosquitoes, the morbidity and mortality rates have increased in low countries until now. However, the best way to control these two diseases is to control vectors, namely mosquitoes. Research has been conducted to determine the bioactive content and larvicidal activity of local plant extracts of North Sulawesi. Materials and Methods: The clove and trumpet flower samples were obtained from Minahasa, while the nutmeg samples were obtained from Sitaro Regency. Empirically, people use plant parts to repel mosquitoes. Extraction of plant simplicia was carried out by the maceration method. Qualitative and quantitative methods carried out the phytochemical content analysis. Qualitative analysis uses Harborneʼs (1996) method while qualitative analysis uses the UV Vis Spectrophotometer method. Toxicity tests were carried out on mosquito larvae developed in the laboratory. Results: The results showed that combining clove leaf extract, nutmeg flesh extract and trumpet flower synergistically increased the bioactive content. Flavonoids increased in the combination of extracts compared to partial extracts. The combination of extracts showed the highest toxicity to mosquito larvae (LC 50 : 22.541 mg LG 1 ), while the lowest was the partial extract of clove leaves with LC 50 (54.965 mg LG 1 ). Conclusion:The combination of extracts showed the best toxicity activity on mosquito larvae. Research on bioactive characteristics and toxicity in adult mosquitoes needs to be carried out in the future.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.