Sex and gender differences influence the health and wellbeing of men and women. Although studies have drawn attention to observed differences between women and men across diseases, remarkably little research has been pursued to systematically investigate these underlying sex differences. Women continue to be underrepresented in clinical trials, and even in studies in which both men and women participate, systematic analysis of data to identify potential sex-based differences is lacking. Standards for reporting of clinical trials have been established to ensure provision of complete, transparent and critical information. An important step in addressing the gender imbalance would be inclusion of a gender perspective in the next Consolidated Standards of Reporting Trials (CONSORT) guideline revision. Uniform Requirements for Manuscripts Submitted to Biomedical Journals, as a set of well-recognized and widely used guidelines for authors and biomedical journals, should similarly emphasize the ethical obligation of authors to present data analyzed by gender as a matter of routine. Journal editors are also promoters of ethical research and adequate standards of reporting, and requirements for inclusion of gender analyses should be integrated into editorial policies as a matter of urgency.
Innovation ecosystems can be constructed around any subject matter. We choose here the topic of gender, which we examine as a component of innovation success. Most analyses of innovation systems tend to assume gender-neutral position with regard to identity and roles of participating actors and their activities. However, real-life innovations can often result in different quality of outcomes for women and men; the innovation potential of highly trained women remains unrealised; and the recent socioeconomic empowerment of women as driver of market needs continues to be ignored. Drawing on latest research evidence from studies of gender issues in science, we show how innovation systems can benefit from adopting more gender sensitive approaches, which recognise the role gender plays in shaping knowledge and market activities. We propose four scenarios for constructing gender sensitive innovation ecosystems based on different gender dynamics that combine scientific understanding of sex and gender differences with improved engagement of women in innovation process, enabled through participatory methods and open and inclusive innovation practices.
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