The SV of the MST showed good reliability and feasibility. The validity is moderate, and the MST could be considered a useful resource for early detection of malnutrition risk.
Purpose
Evaluate the associations of obesity and diabetes with the risk of mortality in critically ill patients infected with SARS-CoV-2.
Materials and methods
This cohort study included 115 adult patients admitted to the ICU with SARS-CoV-2 pneumonia. Anthropometric variables and biochemical (C-reactive protein, ferritin, leukocyte, neutrophils, and fibrinogen) were measured. Multivariate logistic regression analyses were used to investigate the associations.
Results
Mean age was 50.6 ± 11.2 years, 68.7% were male. Median BMI was 30.9 kg/m
2
. All patients had invasive mechanical ventilation. Patients with diabetes had increased risk of mortality with OR of 2.86 (CI 95% 1.1-7.4, p = 0.026); among those patients who, in addition to diabetes had obesity, the risk was de 3.17 (CI 95% 1.9-10.2, p = 0.038). Patients with obesity had 1.25 times greater risk of developing a severe SARS-CoV-2 infection (95% CI 1.09-1.46, p = 0.025). Negative correlation was observed between BMI and the PaO2/FiO2 ratio (r = -0.023, p < 0.05). Obese patients required more days of mechanical ventilation and longer hospital stay compared to non-obese patients.
Conclusions
Diabetes and obesity are risk factors for increasing severity of SARS-CoV-2 infection, and they are both associated with an increase in mortality.
Introduction: Clostridium difficile infection (CDI) causes potentially lethal diarrhea. Objective:To identify the risk factors for mortality in hospitalized patients with CDI. Method: Cross-sectional, retrospective study. The analyzed risk factors were age, comorbidities, nutritional status, past and current use of antibiotics, proton pump inhibitors, steroids, immunosuppressive therapy and chemotherapy, as well as development of acute kidney injury (AKI). Results: Sixty-eight cases were assessed. Mean age was 51.4 ± 19.37 years. Mortality was 22.2 %. Moderate to severe undernutrition (Odds ratio [OR] = 20.
Comparar la efectividad de un plan de alimentación hipocalórico hiperproteico con otro normoproteico sobre la composición corporal, los parámetros bioquímicos y las citocinas inflamatorias en pacientes obesos precirugía bariátrica sometidos a un tratamiento integral. Método: Se estudiaron 76 pacientes con un índice de masa corporal (IMC) ≥ 40 kg/m² previamente a la cirugía bariátrica. Un grupo fue tratado con una dieta hipocalórica hiperproteica y se comparó con una dieta hipocalórica normoproteica. Se evaluaron parámetros bioquímicos, parámetros antropométricos, composición corporal y valores de citocinas inflamatorias en suero al inicio y después de 4 meses de tratamiento. resultados: En ambos grupos se observó una disminución de peso, de IMC y de masa grasa, así como un incremento de la masa muscular respecto al momento basal (p < 0.05), sin diferencias entre los grupos estudiados. No se encontraron cambios en los parámetros bioquímicos ni en las concentraciones séricas de factor de necrosis tumoral (TNF) e interleucina (IL)-6 antes y después de 4 meses de tratamiento, ni entre los grupos evaluados (p > 0.05). Las concentraciones séricas de IL-1β disminuyeron únicamente con la dieta hipocalórica normoproteica (p = 0.02). Conclusiones: La dieta hipocalórica hiperproteica no muestra ventajas en la reducción de peso y grasa corporal, ni en la ganancia de masa muscular, en comparación con la dieta hipocalórica normoproteica en pacientes con obesidad mórbida precirugia bariátrica sometidos a un tratamiento integral.
Objective: To determine the nutritional status and its association with functional capacity in patients with digestive tract cancer. Methods: We retrospectively studied all adult patients hospitalized who were diagnosed as having a cancer of the digestive tract. Nutritional status and functional capacity were assessed. Descriptive statistic and odds ratio were used to determine the association in SPSS 14.0. Results: 57 patients were included, 96% had weight loss. Using subjective global assessment (SGA) as a method of screening, 82.5% of the patients were found malnutrition and by biochemical and immunological test 82% and 65% respectively. Functional capacity was assessed by Karnofsky index, finding that 75.5% of the patients have some activity limitation. Results show an association between malnutrition by SGA and limitation in functional capacity (c2 = 1.56; p = 0.
Recibido en septiembre de 1991; aceptado en diciembre de 1991 RESUMEN El consumo de oxigeno de Callinectes similis sometido a fluctuaciones de salinidad no se modificó significativamente (P > 0.05) y se mantuvo en un intervalo metabólico de 1.23 a 2.08 mg 02.h-l.g-1P.S. que correspondió al tipo de respuesta IV propuesta por Kinne (1971). La tasa de excreción de amonio aumentó significativamente a 0.028 mg N-NHb.h-1.g'lP.S. (P < 0.05) al disminuir la salinidad de 35 a 26o/oo; en el intervalo de salinidad de 1&12-18o/oo se mantuvo constante en 0.021 mg N-NI%,.h'l.g-1P.S.Al incrementar la salinidad a 26o/oo el valor fue de 0.029 mg N-NI-Ib.h-l.g-lP.S., y el núnirno de 0.012 mg N-NI-Ih.h-l.g-1P.S. se obtuvo en 35o/oo. La relación atómica 0:N calculada para C. simifis demostró que las jaibas no fueron afectadas de manera significativa (P > 0.05) por el estrés osmótico al que fueron sometidas, ya que en las salinidades altas catabolizaron carbohidratos y en las bajas utilizaron como los principales sustratos energéticos una mezcla de lipidos y carbohidratos.El patrón de osmorregulación de C. similis fue el típico de un organismo osmoconformador debido a que el medio interno en las salinidades altas se mantuvo ligeramente hiperosmótico e isosmótico en las bajas.
93http://dx.doi.org/10.7773/cm.v18i3.901Ciencias Matinas, Vol. 18, No. 3, 1992 ABSTRACT The oxygen consumption of Callinectes similis was determined under salinity fluctuations. The metabolic rate remained unchanged (P > 0.05) and within a metabolic range of 1
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