SUMMARYPurpose: To evaluate the frequency and the consequences of the co-infection of hepatitis B and C viruses in patients with hepatosplenic schistosomiasis (HSS).Methods: B and C serologic markers, exposure to risk factors, biochemical assays, upper gastrointestinal endoscopies, and abdominal ultrasonograms were evaluated in 101 patients with HSS from 1994 to 1997. Whenever possible, PCR was tested and histopathological studies were reviewed.Results: At least one HBV virus marker was found in 15.8%, and anti-HCV was detected in 12.9% of the subjects. The seropositive subjects tended to be older than the seronegative ones. A history of blood transfusion was significantly related to the presence of anti-HCV. Three (18.75%) out of 16 subjects exposed to B virus were HBsAg positive. Eleven (84.6%) out of thirteen patients who were anti-HCV positive demonstrated viral activity. Patients with ongoing viral infection presented a higher average level of liver aminotransferases, a higher frequency of cell decompensation and a higher rate of chronic hepatitis. Portal hypertension parameters were not influenced by viral exposure. Conclusions:The rate of hepatitis B and C viruses serologic markers observed in the patients with HSS was higher than the control group. The co-infection was responsible for a higher frequency of cell decompensation.
Com o objetivo de avaliar a presença de desnutrição protéico-energética em pacientes hospitalizados, realizou-se um estudo com 57 doentes admitidos consecutivamente para internação na enfermaria de Gastroenterologia Clínica no período de dezembro de 1996 a junho de 1997. A maioria dos pacientes estudados era do sexo feminino (63,2%) e as hepatopatias caracterizavam-se como doença predominante (77,2%), seguidas de enteropatias (10,5%), pancreatopatias (5,3%), gastropatias (3,5%) e outras (3,5%). O estado nutricional foi avaliado objetivamente por meio de medidas antropométricas e bioquímicas e, subjetivamente, por meio de um questionário sistematizado por Detsky. Ambos os métodos foram realizados pelo mesmo observador. Verificou-se que 68,5% dos pacientes apresentavam estado nutricional aceitável, 21,0% desnutrição moderada e 10,5% desnutrição grave. Em vista dos resultados, pode-se concluir que é freqüente a ocorrência de desnutrição ou risco nutricional em doentes hospitalizados com doenças gastrintestinais, sendo que a detecção prévia da desnutrição protéico-energética é de grande importância para que uma terapia nutricional adequada seja oferecida ao paciente.
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