In this study, five new pyrimidine derivatives were synthesized and characterized by characterization methods such as 1 H-NMR, 13 C-NMR, FT--IR and elemental analysis. The corrosion inhibition activity of the synthesized compounds was examined by theoretical calculation using DFT method at the level of B3LYP/6-31G (d,p). According to the calculations, 4-(6-benzoyl-2--benzylidene-3-oxo-7-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-yl)benzoic acid (6) appears to be a good inhibitor for corrosion.
. -The compounds (IV) and (VI) are screened in vitro for their biological activity against four Gram-positive and one Gram-negative bacteria, and against three yeast strains. (VI) is the most effective against the tested organisms but is much less active compared with the standard drugs.-(AKBAS*, E.; BERBER, I.; AKYAZI, I.; ANIL, B.; YILDIZ, E.; Lett. Org.
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