Industrialization of the construction process is increasing around the world due to its potential to improve safety, sustainability, effectiveness, productivity and efficiency. While there has been research into the impacts of various forms of industrialized construction on the construction sector, surprisingly there has been little research into the impacts on subcontractors. The lack of subcontractor's voice in the industrialization debate is important to address since they operate at the coalface of the industry where the impacts of such changes will have a significant impact. The resource based view of the firm (RBV) is used as a theoretical lens to study these potential impacts through interviews with senior executives and managers of six major subcontracting firms which have worked with off-site bathroom pod technologies in Australia. It is found that the key subcontractor resources affected by this off-site technology are human, financial, intellectual and social and that subcontractors will need to pursue strategies which develop new skills, knowledge, networks and deeper supply chain collaborations if they are to turn the potential risks associated with off-site into potential opportunities to achieve competitive advantage.
The hepatic output of triacylglycerol and cholesterol from very-low-density lipoprotein (VLD lipoprotein), and the activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase were compared in the isolated perfused rat-liver preparation and in the intact rat. The output of triacylglycerol and cholesterol from VLD lipoprotein by the perfused liver was stimulated by oleate concomitant with stimulation of hepatic microsomal hydroxymethylglutaryl-coenzyme A reductase activity. In the intact animal treated with Triton WR-1339, the magnitude of secretion of triacylglycerol and cholesterol from VLD lipoprotein coincided with the diurnal rhythm of hepatic hydroxymethylglutaryl-coenzyme A reductase activity, which was maximal at 24:00h and minimal at 12:00h. These observations suggest that the stimulation of the reductase and of the secretion of cholesterol from VLD lipoprotein by non-esterified fatty acids, as observed with the isolated perfused rat liver preparation in vitro, may also be an important physiological mechanism in vivo. Hepatic cholesterogenesis may be stimulated under conditions conducive to the secretion of the VLD lipoprotein, the primary transport form for triacylglycerol in the postabsorptive state.We have reported previously that oleate stimulated the secretion of total triacylglycerol and total cholesterol by the isolated perfused rat liver in vitro.
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