NLR was shown to be better than dNLR in terms of predicting prognosis in patients with breast cancer. However, large prospective studies are required to further demonstrate the prognostic significance of these two values.

Objective: Determination of psychological problems will shed light on the terms of solution and provide support to patients about these problems will ensure the patients' coherence to the treatment and will enhance the benefits they receive from treatment. In this study, we aimed to determine these psychosocial problems and the interactions with each other in colon cancer patients. Methods: In this study, 105 patients with colorectal cancer were included. The forms consist of sociodemographic features, Hospital Anxiety and Depression Scale, European Organization for Research on Treatment of Cancer Questionnaires Quality of Life-C30 and Golombok-Rust Inventory of Sexual Satisfaction questionnaires. Results: Male patients had significantly higher European Organization for Research on Treatment of Cancer Questionnaires Quality of Life-C30 function scales and global quality-of-life scores than female patients. Golombok-Rust Inventory of Sexual Satisfaction scores of female patients were significantly higher than that of male patients. European Organization for Research on Treatment of Cancer Questionnaires Quality of Life-C30 function scales and global quality-of-life scores of the patients with high depression scores were significantly lower, conversely symptom scale scores of the patients with high depression scores were significantly higher than that of the patients with low depression scores. Patients with low anxiety scores had significantly higher European Organization for Research on Treatment of Cancer Questionnaires Quality of Life-C30 function scales and global quality-of-life scores than the patients with high anxiety scores. Symptom scale scores of the patients with high anxiety scores were significantly higher than that of the patients with low anxiety scores. The scores of Golombok-Rust Inventory of Sexual Satisfaction except premature ejaculation and vaginismus were significantly higher in patients with high anxiety scores and a significant difference was determined in touch, avoidance and anorgasm. Conclusions: This study demonstrates that there is a significant association with anxiety/depression symptoms and quality-of-life scores, sexual dysfunction. Sexual dysfunction is significantly more common in patients with high anxiety and depression scores.

No abstract

We aimed to investigate anxiety, depression and sexual satisfaction levels of testicular cancer survivors (TCSs) and compare the scores with healthy men's. The Hospital Anxiety and Depression Scale (HADS), Golombok-Rust Inventory of Sexual Satisfaction (GRISS) and European Organization for Research on Treatment of Cancer Questionnaires Quality of Life-C30 were used. Forty-one TCSs and thirty-eight healthy men were participated in this study. The total HADs scores of TCSs (12.21 ± 8.19) were less than the healthy group (14.44 ± 6.53; p > 0.05). The high depression scores rate was 29.2 and 55.2, and high anxiety scores rate was 24.4 and 28.9 for TCSs and healthy group, respectively. When we evaluated GRISS subscores and anxiety levels, we found significantly increase only in avoidance subscores in the TCSs (p = 0.04). When we evaluated GRISS subscores and depression levels, GRISS subscores of the TCSs who had high depression scores were also high. However, statistical significance was found in satisfaction (p = 0.009), touch (p = 0.04), avoidance (p = 0.01) and erectile dysfunction (p = 0.04) subscores in the TCSs. In the TCSs whose anxiety scores were high, emotional functioning (p = 0.009) and global QoL (p = 0.01) subscores of GRISS was found significantly low. In the TCSs whose depression scores were high, physical (p = 0.01), cognitive (p = 0.04), emotional (p = 0.03), social functioning (p = 0.02) and global QoL (p < 0.001) subscores of GRISS were found significantly low. Anxiety, depression and sexual satisfaction levels of TCSs were found to be similar with the control population.

The results suggest that the elevated NLR predicts poor overall survival following at the time diagnosis for all stage gastric cancer. dNLR was not independently associated with overall survival. There is insufficient evidence to the assesment of TIL by a nonspesific method. Therefore further studies is required, to confirm our hypothesis in larger patient cohorts.

ÖZETAmaç: Bu çalışmada premenapozal meme kanserli hastalarda tamoksifenin etkilerini, anksiyete, depresyon, yaşam kalitesi ve cinsel doyumları açısından belirlemek amaçlandı. Yöntem: Adjuvan tamoksifen kullanan 67 premenapozal meme kanserli kadın çalışmaya dahil edildi ve veriler yüzyüze görüşme sırasında bir dizi formlar kullanılarak toplandı. Çalışmada, sosyo-demografik bilgi formu, Hastane Anksiyete ve Depresyon Ölçeği (HADS), Golombok-Rust Cinsel Doyum Ölçeği (GRCDÖ) ve Yaşam Kalitesi Ölçeği (EORTC-QoL-C30) uygulandı. Bulgular: Hastaların %46.26'sında depresyon, %40.29'unda yüksek seviyede anksiyete saptandı. Fiziksel, rol, bilişsel, duygusal ve sosyal işlevsellik ve global yaşam kalitesi alt skorları, anksiyete seviyeleri yüksek hastalarda düşük bulundu. Depresyon skorları yüksek olan hastalarda, fiziksel işlevsellik ve global yaşam kalitesi alt skorları dışındaki tüm işlevsellik skalaları istatistiksel olarak düşük bulundu. Anksiyete seviyeleri yüksek olan hastalarda, tüm GRCDÖ altskorları yüksekti. Fakat istatiksel olarak fark sadece iletişim, doyum, dokunma ve anorgasmi alt skorlarında gözlemlendi. Depresyon seviyeleri yüksek olan hastalarda tüm GRCDÖ alt skorları yüksekti. Fakat istatiksel olarak fark sadece iletişim, doyum, dokunma ve anorgasmi alt skorlarında gözlemlendi. Sonuç: Meme kanseri ve uzun dönemli adjuvant tedaviler, hastaların sadece klinik durumlarını değil psikososyal ve psikoseksüel durumlarını da etkilemektedir. Bu nedenle, bu durumların farkında olunması, meme kanserli hastaların yaşam kalitesini yükseltecektir. Anahtar Kelimeler: Depresyon; Anksiyete; Yaşam kalitesi; Cinsel doyum; Meme kanseri ABSTRACT Objective: In this study, we aimed to determine the effects of tamoxifen on premenopausal breast cancer patients in terms of anxiety, depression, quality of life (QoL) and sexual satisfaction. Methods: Sixty-seven premenopausal patient with breast cancer using adjuvant tamoxifen were participated in the study and the data were collected by using a series of forms that completed during face-to-face interviews. The form that consists of socio-demographic characteristics of the pateints, the Hospital Anxiety and Depression Scale (HADS), Golombok-Rust Inventory of Sexual Satisfaction (GRISS) and European Organization for Research on Treatment of Cancer Questionnaires Quality of Life-C30 (EORTC-QoL-C30) were applied to the participants. Results: We determined that 46.26% of the patients had depression and 40.29% had high anxiety levels. Physical, role, cognitive, emotional and social functioning and global QoL subscores were also found to be low in patients whose anxiety levels were high. In patients whose depression scores were high, all the functioning scales, except physical functioning scale and global QoL subscores of EORTC-QLQ-C30 were found statistically significantly low. All the GRISS subscores were higher in the patients whose anxiety levels were high. However, statistical significance was observed only in the communication, satisfaction, touch and anorgasmi subscores. All the GRIS...