The 6mWT and 2mWT have excellent test-retest reliability as well as moderate construct validity for the evaluation of functional exercise capacity patients with MG. Muscle Nerve, 2018.
Linguistic, reliable, and valid secondary efficacy measures are important in clinical settings and studies. The aim of the study is to report test–retest reliability and construct validity of Turkish version of Myasthenia Gravis-Activities of Daily Living Scale (MG-ADL-T) in Myasthenia Gravis (MG) patients. Fifty-two ocular and generalized individuals with MG, applying to rehabilitation center, were included in the study. MG-ADL-T, MG quality-of-life questionnaire (MG-QoL), MG composite (MGC), quantitative MG score (QMGS), and pulmonary function test were administered. Reliability was assessed with intraclass correlation coefficient (ICC) and Cronbach’s alpha. Spearman correlation test and receiver operating characteristic (ROC) analysis were performed for construct validity. MG-ADL-T had fair internal consistency (Cronbach’s α = .67), excellent test–retest reliability (ICC = 0.96) and moderate construct validity (MG-QoL, r = 0.59; QMGS, r = .58; MGC, r = .68). MG-ADL, a unique scale that evaluates activities of daily living (ADL), has good test–retest reliability and construct validity in Turkish MG patients.
Objectives: To investigate the correlations between the 6-minute walk test and disease severity, pulmonary functions, and respiratory muscle performance in patients with generalized myasthenia gravis)MG(and to determine whether MG disease severity, pulmonary functions, and respiratory muscle performance contribute to 6-minute walk test distance in generalized MG. Methods: This cross-sectional trial was conducted at Hacettepe University in Ankara, Turkey. The study was carried out from February to August 2017. Twenty-eight class II-III MG patients participated in the study. Patients' disease severity was determined with the Myasthenia gravis composite scale. All participants underwent the 6-minute walk test, pulmonary function tests, and respiratory muscle strength and endurance assessment. Results: Approximately 40% of patients' expiratory muscle strength were under the lower limit of normal. Multiple linear regression analysis revealed that the percentage of predicted expiratory muscle strength that patients reached were significant and independent predictor of percentage of 6-minute walk test distance that patients reached according to reference values)R2=0.493, F [1-27]=25.275, p<0.001(. Conclusion: Expiratory muscle strength is a significant determinant of functional exercise performance in generalized MG with mild or moderate weakness affecting muscles other than the ocular muscles.
The study aimed to examine hamstring-quadriceps muscle activations of the supine bridge and reverse plank exercises that are performed for both improving the overall body strength and contributing to the treatment in the process following an injury on different grounds. Methods: Ten participants (four males and six females, age=26.70±3.02 years) without regular sports habits were included in the study. Bilateral supine bridge and bilateral reverse plank exercises were practiced randomly on stable and unstable grounds. In the study, muscle activation values of vastus medialis (VM), vastus lateralis (VL), biceps femoris (BF) and semitendinosus (SEM) muscles of the participants were examined. Along with the muscle activation that occurred during the exercise, hamstring (BF+SEM)/quadriceps (VM+VL) ratio was also determined (H:Q). Results: The lowest co-activation ratio (most balanced H:Q activation) was observed on stable ground bridge exercise (5.83±4.04), and the largest co-activation ratio (hamstring dominant activation) was observed on stable ground plank exercise (8.84±6.60). No significant difference was found between exercises at H:Q co-activation ratio (p>0.05). A statistically significant difference was found in the quadriceps and hamstring group in terms of exercise and difference ground in favor of plank (p<0.05). Conclusion: Reverse plank exercise has greater agonist muscle activation than the supine bridge. Therefore, it is thought that bridge exercise could be advised in the rehabilitation process that necessitates a high level of balance, especially in co-activation ratio. Further study with various clinical problems may direct the process.
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