We have performed the retrospective comparison of the parameters of physical development (circumference of head and chest, body weight and length), dynamics of laboratory tests, death rate in 103 HIV-positive and 77 HIV-exposed children. The majority of the studied parameters were within the normal range. The differences between the groups revealed in the follow up might be used for HIV status prognosis.
The present work analyzes the records of perinatal and infant autopsies of 25 children under 1 who died in the period from September 1998 to January 2010 and whose mothers were HIV-positive. According to the study, various viral infections are the most common causes of death among HIV-exposed children (36 %). Two HIV-exposed children were diagnosed as HIV-positive (they revealed RNA HIV). The cause of death of both the children was a generalized viral infection of unspecified etiology. One of the two children observed concomitant disease - Kaposi's sarcoma. The structure of the mortality rate in the HIV-exposed children did not differ from that in children born by HIV-negative mothers.
The paper presents data on the prevalence of markers of certain opportunistic infections in both HIV-positive children infected via vertical transmission and registered at the HIV/AIDS outpatient consultative ward of the Gomel Regional Infectious Clinical Hospital and in HIV-negative children. The HIV-positive children (43 %) in comparison to the HIV-negative children (26 %, p = 0.008) detected EBV DNA significantly more often. However, the group of the HIV-negative children revealed CMV Ig G more often (50 % vs. 12 % in HIV-positive, p = 0,02). HSV1/2 DNA in the study groups of the children was not detected. The children did not detect Ig M to toxoplasmosis atibodies). CMV, HSV 1/2.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.