Erroneous urine tests for sugar can result from many causes. The Clinitest method carried out in the usual recommended way (five drops of urine) is accurate in the 0 to 2 per cent sugar concentration range. Over 4 per cent, there is a reversal of color which can be mistaken for 0.75 or 1 per cent and which is referred to as “pass through.” When two drops of urine are used instead of five, the range of Clinitest change is extended from 0 to 5 per cent and the “pass through” delayed until a concentration over 10 per cent sugar is reached. In 191 urines from diabetic children, the confusing “pass through” was found to occur seventy times when the urine was tested by the “five-drop method.” It did not occur in testing the same urines using the “two-drop method.” Quantitative chemical analysis established the range of these two methods. It is recommended that the “two-drop method” should replace the “five-drop method.”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.