The rectal-axillary temperature difference (R-A) was measured in the morning, at midday, and in the afternoon on 1,519 occasions in 1,149 children from birth to 5 years old. Of these, 302 children were febrile (rectal temperature > or = 38 degrees C) and 847 were afebrile. A wide range in R-A was found for each individual in both groups. The magnitude of this difference was not associated with sex or age. In febrile children, the R-A was significantly greater (P < .0001) at the apparent onset of fever (1.04 +/- 0.25 degrees C) than later, when fever had been present for at least two hours (0.53 +/- 0.22 degrees C). These findings indicate that it is impossible to find a standard number by which to convert axillary to rectal temperature or vice versa. Furthermore axillary temperature may be relatively low or even "normal" despite an elevated rectal temperature at the onset of fever.
Osteopenia is not uncommon in children and adolescents with IDDM. In 10 children with IDDM and osteopenia the administration of 1 alpha-OHD3 for 1 year corrected bone loss.
In 1979 a national screening programme for congenital hypothyroidism (CH) was introduced in Greece. Treatment with L-thyroxine was started immediately after confirmation of the diagnosis, at a median age of 28 days. A standardized development test (Griffiths) was given to a group of CH infants and to healthy controls at the ages of 5-7, 11-13, 17-19, and 23-25 months. Thirty-three infants with CH were also studied at the age of 35-37 months. The mean developmental quotient of CH infants was 103.8 +/- 12.0, 100.9 +/- 10.1, 103.3 +/- 7.1 and 99.8 +/- 10.2 from the ages of 5-7 to 23-25 months, and was not statistically different from those of the controls. Statistical analysis showed no significant differences between athyreotic children and those with an ectopic gland. Our findings show that the prognosis for psychomotor development of children with CH is quite good, provided that treatment starts in the first 6 weeks of life.
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