The pilot study was conducted to assess the effectiveness of the sensorimotor respiration control (SRC) method based on the biological feedback principle, in the complex correction of respiratory dysfunction and asthenia in 48 patients with Parkinson's disease. Initially, in all patients, there was identified a significant correlation between subjective respiratory disorders, biomechanical changes in the respiratory pattern and the respiratory cycle (r=0.81), and varying degrees of asthenia. The severity of respiratory dysfunction (r=0.76), motor deficit (r=0.71), asthenia (r=0.81) and anxiety-depressive manifestations (r=0.63) have a significant impact on the decline of the quality of patient's life. During course of treatment, there was a significant improvement in the parameters of the respiratory cycle, asthenia, quality of life and the psycho-emotional state of the patients (r<0.05), the normopnoic version of the respiratory pattern was reached in 62.5 % of patients (p<0.05), and the physiological type of the respiratory pattern was achieved in 41.7 % of patients.
The article is devoted to the analysis of the pathogenetic mechanisms of the formation of alcoholic lesions of the peripheral nervous system. Various clinical forms of alcoholic polyneuropathy are considered, ways to diagnose using modern instrumental and laboratory methods are proposed. The authors analyze the main ways of forming a therapeutic strategy, consider groups of drugs used to treat alcoholic polyneuropathy. The data of own clinical experience of using the preparation of thioctic acid are given.
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