Aim:The purpose of this work was to study the dynamics of structural manifestations of acute cases of postpartum endometritis in cows.Materials and Methods:The light and electron microscopy methods were used when studying structural changes in the endometrium in case of postpartum endometritis in seven cows. Sections of endometrial specimens for light microscopy, 5-7 µm thick, were stained with hematoxylin and eosin and also by Van Gieson’s. For electron microscopy, semi-thin sections were stained with Azur-2 in combination with basic fuchsin, as well as contrasting by lead citrate and uranyl acetate.Results:As a result of the study, we have established the following: Necrobiosis of the epithelial layer of the mucosa, cellular infiltration with shaped elements of blood in the functional layer, swelling of the cells of the uterine gland, and single microbial cells on the surface of the mucosa. We have noted edema of the stroma of the functional layer of the endometrium, swelling of the epithelial layer of the endometrial mucosa, and swelling of fibroblastic and lymphoid cells. Ultrastructural changes in endometrial cells in case of acute postpartum endometritis in cows are accompanied by the destruction of microvilli on the apical surface of the epithelium, an abundance of coccal microflora on the surface of the epithelium, necrobiosis of epithelial cells, and partial edema of the nucleus, and cytoplasm of the histiocyte.Conclusion:We had established that acute purulent-catarrhal dystrophic processes were observed in the structural organization of the endometrium. In the depth of catarrhal mucus on the surface of the endometrium, there was an abundance of bacterial flora, with diplococci being prevalent. In ultrastructural organization of the endometrium, we observed deep dystrophic and necrobiotic processes in the parenchyma and endometrial stroma, as well as exudative processes with a change in the integrity of the microcirculatory bed. Thus, to prevent an inflammatory process from turning into a latent form, it is necessary to detect acute postpartum endometritis promptly using diagnostic methods taking into account the obtained parameters of the dynamics of structural changes in the uterine tissues.

Background and Aim: The present study investigated the influence of liver tumor structure on life expectancy in dogs. Diseases of the liver comprise 5-25% of all non-communicable diseases in dogs, and primary hepatic tumors account for 0.6-1.3% of tumors. This research aimed to study the post-operative life span of animals with primary or metastatic tumors of the liver. Materials and Methods: During the study period, 7124 oncological operations were performed in our clinic. In total, 128 liver tumors were detected in live animals, while 323 were detected posthumously. Forty animals underwent surgery for various liver tumors. In dogs with primary liver tumors, the average age was 11.9 years and the average body weight was 15.5 kg, while in dogs with liver metastases, the mean age was 11.4 years and the average body weight was 24 kg. Results: The ratio of males to females among dogs with primary liver tumors was about 1:1 (ten females and nine males), while that among dogs with metastatic liver damage was clearly predominantly female (14 females and two males) because females often undergo surgery for cancerous mammary glands or ovaries. Conclusion: The size of tumors and the number of affected lobes had a significant effect on the post-operative life span. With a tumor size of <5 cm and a lesion covering less than two lobes of the liver, life expectancy was significantly longer and the prognosis was more favorable. In cases of large tumors or those affecting more than two lobes, life expectancy was significantly reduced and the prognosis was cautious to unfavorable.

Cosmic ray data collected by the KASCADE air shower experiment are competitive in terms of quality and statistics with those of modern observatories. We present a novel mass composition analysis based on archival data acquired from 1998 to 2013 provided by the KASCADE Cosmic ray Data Center (KCDC). The analysis is based on modern machine learning techniques trained on simulation data provided by KCDC. We present spectra for individual groups of primary nuclei, the results of a search for anisotropies in the event arrival directions taking mass composition into account, and search for gamma-ray candidates in the PeV energy domain.

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Background and Aim: It is known that during the early postpartum and lactation periods in dairy cows, metabolic disorders develop, that is, ketosis, which can lead to secondary damage to internal organs. Therefore, it is important to address the issues of changing the lactating cows' clinical, laboratory, and physiological parameters regarding the development of hepatocardial syndrome. This study aimed to provide clinical and diagnostic justification for developing hepatocardial syndrome in highly productive dairy cows. Materials and Methods: The study was conducted on 20 black and white cows in the early postpartum period (7–10 days after birth), with a milk production level of >4500 kg of milk during the previous lactation period, a positive result in the formol colloid sedimentary test, the presence of deafness and splitting of heart sounds, changes in the size, or increased pain sensitivity of the percussion field of the liver. Clinically healthy dairy cows in the early postpartum period were used as controls (n = 24). Clinical, electrocardiographic, echocardiographic, and biochemical parameters were also evaluated. Results: Dairy cows with hepatocardial syndrome developed arterial hypertension and sinus tachycardia, which led to a significant decrease in PQ and QT intervals at ECG. A significant increase in the diastolic size of the interventricular septum, systolic size of the free wall of the left ventricle, and diastolic and systolic sizes of the left ventricle and a significant decrease in the shortening fraction of the left ventricular myocardium were observed in the cows due to the development of hepatocardial syndrome. The affected cows demonstrated a significant increase in serum activity of gamma-glutamyl transferase, alanine aminotransferase, lactate dehydrogenase, creatine phosphokinase, alkaline phosphatase, troponin, malondialdehyde, diene conjugates, and ceruloplasmin and a decrease in glucose concentration. In addition, they demonstrated decreased activity of superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase. Conclusion: Hepatocardial syndrome in dairy cows occurs due to ketosis, characterized by arterial hypertension, sinus tachycardia, a moderate decrease in myocardial contractility, oxidative stress, and cytolysis of cardiomyocytes and hepatocytes. Therefore, the control and prevention of the development of hepatocardial syndrome will make it possible to maintain the productive health and longevity of dairy cows.

The textbook considers the issue of assessing the heat and humidity state of air in the processes of its processing in various systems, provides requirements for air protection means, taking into account their environmental friendliness, shows ways of energy saving in cooling, heating and year-round air conditioning systems, as well as when protecting the atmosphere from harmful emissions. The way of energy saving with individual thermal protection of the operator by means of local cooling during air treatment in an irrigated intensified nozzle is shown and recommendations for reducing its material consumption are developed. The method and means of reducing the toxicity of emissions of tractor internal combustion engines during its operation in rooms of limited volume by water vapor humidification of the fuel-air mixture are demonstrated. The ways of noise reduction of air protection systems are shown. Meets the requirements of the federal state educational standards of higher education of the latest generation. It is intended for students studying in the specialties "Ground transport and technical means", "Operation of transport and technological machines and complexes", "Power engineering", "Ground transport and technological complexes", "Refrigeration, cryogenic equipment and life support systems", "Technosphere safety", "Ecology and nature management".

Radio detection of air showers produced by ultra-high energy cosmic rays is a cost-effective technique for the next generation of sparse arrays. The performance of this technique strongly depends on the environmental background, which has different constituents, namely anthropogenic radio frequency interference, synchrotron galactic radiation and others. These components have recognizable features, which can help for background suppression. A powerful method for handling this is the application of convolution neural networks with a specific architecture called autoencoder. By suppressing unwanted signatures, the autoencoder keeps the signal-like ones. We have successfully developed and trained an autoencoder, which is now applied to the data from Tunka-Rex. We show the procedures of the training and optimization of the network including benchmarks of different architectures. Using the autoencoder, we improved the standard analysis of Tunka-Rex in order to lower the threshold of the detection. This enables the reconstructing of sub-threshold events with energies lower than 0.1 EeV with satisfactory angular and energy resolutions.