Postpartum dysgalactia syndrome (PDS) is an economically important condition in sows. The syndrome is characterized by a reduced milk and colostrum production within 12 to 48 hours post partum. The objective of this study was to determine whether preventive treatment with ketoprofen (Ketofen®10%, Merial, Belgium) has a positive effect on the subclinical form of PDS. Sows (n = 39) were randomly divided into two groups: one served as control group whereas the other was treated intramuscularly with ketoprofen within twelve hours after parturition. During the first 24 hours postpartum, the rectal temperature of the sows decreased (-0.43 ± 0.13 °C) in the ketoprofen group. In the control group, an increase was seen (+0.07 ± 0.02 °C) (P < 0.05). There was no significant effect on back fat loss of the sows, weight gain of the piglets (n = 541) and survival rate. In conclusion, a single intramuscular administration of ketoprofen to sows shortly after farrowing decreased rectal temperature but did not improve the performance of the piglets.
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