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Background and Objectives: The National Cancer Database (NCDB) captures nearly 70% of all new cancer diagnoses in the United States, but there exists significant variation in this capture rate based on primary tumor location and other patient demographic factors. Prostate cancer has the lowest coverage rate of all major cancers, and other genitourinary malignancies likewise fall below the average NCDB case coverage rate. We aimed to explore NCDB coverage rates for patients with genitourinary cancers as a function of race. Materials and Methods: We compared the incidence of cancer cases in the NCDB with contemporary United States Cancer Statistics data. Results: Across all malignancies, American Indian/Alaskan Natives subjects demonstrated the lowest capture rates, and Asian/Pacific Islander subjects exhibited the second-lowest capture rates. Between White and Black subjects, capture rates were significantly higher for White subjects overall and for prostate cancer and kidney cancer in White males, but significantly higher for bladder cancer in Black versus White females. No significant differences were observed in coverage rates for kidney cancer in females, bladder cancer in males, penile cancer, or testicular cancer in White versus Black patients. Conclusions: Differential access to Commission on Cancer-accredited treatment facilities for racial minorities with genitourinary cancer constitutes a unique avenue for health equity research.

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This systematic review evaluated the combined effects of obesity and surgical approach on periprosthetic joint infection (PJI) rates after total hip arthroplasty (THA). Wound complication and PJI rates were elevated among patients with body mass index (BMI) of 30 kg/m 2 or greater and 35 kg/m 2 or greater, respectively, with the direct anterior approach (DAA). A BMI of 30 kg/m 2 or greater also increased the risk of PJI with the posterior approach. Patients with BMI of 30 kg/m 2 or greater undergoing anterolateral approach THA did not have increased risk of PJI. Patients with elevated BMI (≥30 kg/m 2 ) are at risk for PJI, regardless of approach. Patients undergoing DAA THA who have BMI of 35 kg/m 2 or greater may have an increased risk of PJI compared with those undergoing THA with other approaches. [ Orthopedics . 2022;45(2):e67–e72.]

Interstitial cystitis/bladder pain syndrome is a poorly understood chronic pain condition. While patients experience chronic pain in their bladders and changes to their urinary habits, they also commonly experience widespread pain and issues beyond their bladder. The cause(s) of these symptoms is not well understood. Our research found evidence that patients with interstitial cystitis commonly have damage/thinning to the nerves in their skin, which is associated with being chronically fatigued. This finding may explain some of the widespread symptoms these patients experience.

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