1,533 confirmed cases of Covid-19 were recorded in Central Java until June 3, 2020. It is estimated to increase every day. However, reports on the epidemiological characteristics of confirmed cases of Covid-19 are still limited. The purpose of this study is to describe the confirmed case of COVID-19 in Central Java. This study uses descriptive quantitative design, in which we describe 1,533 cases based on patient characteristics, history of comorbidities, travel history and symptoms. The data of patients processed with descriptive statistical analysis from the Department of Health of Central Java. The results of the study showed that of 1,533 confirmed cases, 64.05 % were male patients and 46.7% aged 19-44 years. From 102 death cases, it is dominated by men (64.7 %) and the elderly ≥60 years (50 %). The highest IR is the City of Semarang with IR of 17.9 / 100,000 population. The most common history of comorbidities is hypertension and diabetes mellitus with a total of 5 cases each. Cases with a domestic travel history had the highest number of 34.1% while those without a travel history amounted to 65%. The symptoms experienced by most confirmed patients are Cough, Fever with 10.8%. Thus, it was concluded that confirmed cases in Central Java were spread in 35 cities / regencies with high number. It is necessary to conduct a detailed confirmed case reports to control the policy on Covid-19 prevention and countermeasures in Central Java.

Objective: This study aimed to determine a target of action of bruceine A on the basis of its morphological and histological effects on the larvae of Aedes aegypti Linnaeus.Methods: Bruceine A was isolated from Brucea javanica (L.) Merr. seeds in accordance with the Mangungsong method. Larvae of A. Aegypti (L.) in instar III to the beginning of instar IV were treated with various concentrations of bruceine A. The negative control group did not receive any treatment, whereas the positive control group received 1 ppm temefos. Dead larvae were collected after 24 h of treatment for the examination of morphological and histological changes.Results: The negative control group did not exhibit any morphological and histological changes. Larvae treated with bruceine A, however, had visible damaged heads, cuticles, digestive and respiration tracts, respiratory siphons, and setae, and they were smaller than normal larvae. Larvae treated with temefos exhibited gastrointestinal damage, narrowed breathing tubes, cuticle damage, and detached/damaged seta feathers. The necrosis of gastrointestinal epithelial cells was the major histological change exhibited by larvae treated with various concentrations of bruceine A or 1 ppm temefos.Conclusion: The targets of action of bruceine A in A. aegypti (L.) larvae are the head/caput, cuticle, setae, siphon, and gastrointestinal and respiratory tracts.

Background: According to UNICEF, half of all deaths of children are caused by malnutrition. The conventional anthropometric index to measure nutritional status is unable to measure the overall prevalence of malnutrition and multiple malnutrition. The solution is to measure it using the Composite Index of Anthropomeric Failure (CIAF). The aim of the study was to analyze the factors that affect the nutritional status of children aged 0-23 months based on Composite Index of Anthropomeric Failure (CIAF).Methods: This research was an observational analytic study with cross-sectional study design. This research was conducted in the working area of Karangayu Health Center with 231 study sample of mothers who have 0-23 months old children (population used as sample). Chi-square and fisher exact test were used as statistical test.Result: Factors associated with the nutritional status of children aged 0-23 months based on the Composite Index of Anthropometric Failure (CIAF) were the age of the child (p=0,029); birth length (p=0.005); maternal age during pregnancy (p=0.002); maternal height (p=0.025); gestational age of maternal (p=0.049). While factors unassociated were gender (p=0.997), birth weight (p=0.316), nutritional status of the mother during pregnancy (p=0.232), maternal employment (p=0.614), and education level (p=0.951).Conclusion: Age of child, birth length, maternal age during pregnancy, mother’s height, and gestational age of maternity mothers were factors associated with nutritional status of 0-23 months old children based on CIAF. A dominant factor that affected the nutritional status of children aged 0-23 months was the mother's age during pregnancy.

Background: The assessment from the patient's perspective is the assurance of TB service’ quality to achieve the "End TB" target. The information regarding TB services’ quality assessment in the dimensions of QUOTE TB Light is not widely found.Aims: The study aims to review TB services' quality from the patients’ perspective in the 7 dimensions of QUOTE TB Light.Methods: This literature review study searched from 3 databases, namely PubMed, Science-Direct, and Google Scholar since July - October 2020. The inclusion criteria were research on TB services quality, patients’ perspective, and patient assessment of 7 dimenssion. Articles assessed the other health services’ quality and published before January 2015 was excluded.Results: A total of 7 from 89 articles found were selected for review. The patients’ assessments are based on their experiences or satisfactions. Most of the studies are satisfied with service availability, communication, patient-provider interactions, competence, and affordability. The patients’ dissatisfactions about infrastructure and stigma acquired during treatment.Conclusion: Infrastructure and stigma are assessed negatively. The continously evaluation and training for health workers need to be improved so they can serve patients well. The patients’ perspectives can be the major consideration for providers to enhance the TB services’ quality.Keywords: Quality of TB services, QUOTE TB Light, patients’ perspectives, Tuberculosis

Hypertension is the silent killer, one of the main risk factors for heart attack and stroke. Based on Riskesdas data in 2018 the prevalence of hypertension blood pressure measurements in Indonesia increased by 8.3%, from 25.8% (in 2013) to 34.1% (in 2018). The prevalence of hypertension in Jambi Province based on the results of the 2013 Riskesdas was quite high at 24.6%. In Sarolangun Regency primary hypertension was second only to ARI, which was 16.3%. But the study of the characteristics of patients with primary hypertension in Sarolangun District is still limited. The purpose of this study was to determine the characteristics of patients with primary hypertension, especially the age and sex of patients in Sarolangun District in 2016. The method of this study was an observational descriptive study, with a case control study design. The sampling technique uses total sampling.

AbstrakKota Semarang merupakan kota dengan kasus DBD tertinggi di Jawa Tengah dengan Kecamatan Ngaliyan sebagai daerah endemis tertinggi. Upaya pengendalian DBD sampai saat ini belum memberikan hasil memadai, sehingga diperlukan cara lain untuk membantu program pemberantasan vektor DBD, antara lain dengan Teknik Jantan Mandul atau yang lebih dikenal Teknik Serangga Mandul (TSM). Penelitian ini bertujuan untuk menganalisis tingkat kepadatan populasi nyamuk dan pendapat/persepsi masyarakat di Kelurahan Ngaliyan terhadap penggunaan TSM dalam pengendalian vektor Demam Berdarah Dengue (DBD). Penelitian ini merupakan penelitian deskriptif analitik dengan desain study cross sectional. Pengambilan data dilakukan dengan observasi nyamuk Aedes aegypti dan wawancara mengenai pendapat masyarakat. Analisis data menggunakan analisis bivariat dengan wilcoxon sign test. Dari hasil penelitian ini dapat disimpulkan bahwa penggunaan TSM di kelurahan Ngaliyan dapat menurunkan tingkat kepadatan populasi nyamuk Aedes aegypti serta ada perbedaan pengetahuan dan sikap masyarakat sebelum dan setelah penggunaan TSM (p= 0.000 < 0.05) Kata Kunci: teknik serangga mandul, kepadatan populasi nyamuk, persepsi masyarakat, Aedes aegypti Abstract Semarang city is a city with the highest dengue cases in Central Java with the District Ngaliyan as the highest endemic areas .Until now, dengue control efforts have not provided adequate results , therefore we need other measures, one alternative is using Technique Male Infertility or better known as Sterile Insect Technique ( TSM ). This study aimed to observe the population density of mosquitoes and how public opinions about TSM after using insect technique. This research is descriptive analytic with cross sectional design study. Data is collected by the Aedes aegypti mosquito observation and interviews regarding public opinion . Data analysis using bivariate analysis with the Wilcoxon sign test. Based on the results it can be concluded that the use of TSM in the village Ngaliyan can reduce the population density of Aedes aegypti , and there are differences in knowledge and attitudes before and after the use of TSM ( p = 0.000 < 0.05).

The mRNA 1273 vaccine by Moderna © has recorded to be94.1% effective against laboratoryconfirmed Covid-19 infection. Health care workers in Indonesia are receiving third-booster vaccine by Moderna after the two doses of virus-inactivated vaccine. Further evaluation of Covid-19 mRNA vaccine post-injection effects on health care workers is necessary. This present study asssessed the postimmunization adverse events tohealth care workersin the Port Health Office of Semarang.This was a retrospective, cross-sectional, observational study aimed to the HCWs, both staff and non-staff, of the Port Health Office of Semarang.We identified and analyzed the adverse effects on 132 workers who had been receiving third-mRNA booster vaccine by Moderna. About 37.8% (50 out of 132)respondents experienced adverse events after receiving third-booster vaccine by Moderna. Among them, female workers (62%) had more incidents compared to males (38%). the most common symptoms were localized painon injected arm (100%), fatigue (44%), fever (42%), myalgia (38%), and chills (30%). Other symptoms like night sleep issue, diarrhea, nausea, an headacheswere also reported.The mRNA 1273 vaccine by Moderna © injection as booster provides several severe but not life-threatening symptoms, most of the emerging cases are fatigue and fever and and possibly correlated with gender.

INTISARI: Latar Belakang: Tikus merupakan hewan liar yang sering dikaitkan dengan kehidupan manusia dan merugikan di berbagai bidang, salah satunya adalah kesehatan. Di bidang kesehatan, tikus dapat menjadi reservoir beberapa patogen penyebab penyakit pada manusia, salah satunya adalah urine tikus yang dapat menyebabkan leptospirosis. Berdasarkan data Dinas Kesehatan Kota Semarang, populasi tikus tertinggi di Kecamatan Tembalang pada tahun 2019 terdapat di Desa Tandang dengan jumlah tertangkap 164 ekor. Selain itu, pada tahun 2018 terdapat 4 kasus Leptospirosis di Desa Tandang dan Leptospirosis merupakan penyakit infeksi tertinggi di Desa Tandang, Kecamatan Tembalang, Kota Semarang. Tujuan: Menghitung kepadatan populasi tikus hasil perangkap yang berhasil dilakukan dan mengidentifikasi spesies tikus yang ditangkap di Desa Tandang Kota Semarang. Metode: Jenis penelitian yang digunakan adalah penelitian deskriptif dengan metode cross sectional. Sampel dalam penelitian ini adalah seluruh mencit yang ditangkap di RW 03 Desa Tandang Kecamatan Tembalang Kota Semarang dengan menggunakan 100 perangkap hidup selama 2 hari berturut-turut. Hasil: Kepadatan relatif tikus (keberhasilan perangkap) di Desa Tandang adalah 28,1%. Jenis tikus yang paling banyak ditangkap di Desa Tandang adalah Rattus tanezumi yaitu 10 (55,6%) dan Rattus Norvegicus yaitu 8 (44,4%). Sepuluh tikus jantan (55,6%) ditangkap dari 8 tikus betina (44,4%). Kesimpulan: Keberhasilan perangkap di desa Tandang sebesar 28,1% atau termasuk dalam kategori padat. Kepadatan relatif tikus (keberhasilan perangkap) di desa Tandang adalah 28,1%. Jenis tikus yang paling banyak ditangkap di Desa Tandang adalah Rattus tanezumi yaitu 10 (55,6%) dan Rattus Norvegicus yaitu 8 (44,4%). Sepuluh tikus jantan (55,6%) ditangkap dari 8 tikus betina (44,4%). Kesimpulan: Keberhasilan perangkap di desa Tandang sebesar 28,1% atau termasuk dalam kategori padat. Kepadatan relatif tikus (keberhasilan perangkap) di desa Tandang adalah 28,1%. Jenis tikus yang paling banyak ditangkap di Desa Tandang adalah Rattus tanezumi yaitu 10 (55,6%) dan Rattus Norvegicus yaitu 8 (44,4%). Sepuluh tikus jantan (55,6%) ditangkap dari pada 8 tikus betina (44,4%). Kesimpulan: Keberhasilan perangkap di desa Tandang sebesar 28,1% atau termasuk dalam kategori padat.