The sera of hamsters carrying tumours induced by injection of TSV5Cl2 cells and the sera of animals immunized with these cells or with SV40 itself or its purified capsids have a slow cytotoxicity activity in the presence of fresh guinea pig complement on SV40‐transformed cell strains of any origin. The responsible antigen is dependent on the SV40 genome and is associated with the cytoplasmic membranes of the transformed cells. By means of absorption of the antisera with subcellular fractions it has been correlated with antigen “C” present in the cytoplasm of SV40‐transformed cells. It is different from antigen “S” shown by the immunofluorescence test, and its relation with TSTA is discussed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.