Introduction. Laryngeal schwannomas are rare benign neurogenic tumors. They are usually localized in the supraglottic portion of the larynx.Case report. We report a rare case of laryngeal schwannoma with a focus on clinical presentation, diagnosis and management. A 61-year old male patient with a 3-year history of hoarseness underwent telescopic examination which revealed an oval submucosal tumefaction of the left ventricular fold extending over the left vocal fold toward the right ventricular fold. Multi-slice computed tomography showed a 22x15mm well defined, oval heterodense mass in the region of the left ventricular fold, extending toward the left vocal fold and the posterior commissure of the larynx, with signs of initial compression lesion of the thyroid cartilage. Biopsy and histopathology report revealed a primary benign encapsulated mesenchymal tumor, while immunohistochemistry analysis confirmed schwannoma diagnosis. The patient underwent tracheotomy and left hemilaryngectomy, with complete removal of the tumor. There were no signs of recurrence at the six-month follow-up. Conclusion.Schwannomas are rare among benign tumors of the larynx and might grow for years before being diagnosed. Biopsy with histopathology analysis is used to confirm the diagnosis of laryngeal schwannoma, although extreme care should be taken during biopsy.Treatment consists of complete surgical excision, while surgical approach depends on the size and localization of the tumor, as well as on the presence of a peduncle.
Background/Aim. Lymphomas are malignant diseases of lymphocytes. There are two basic types of lymphoma: Hodgkin's lymphoma (HL) whose main characteristic is the presence of Reed-Sternberg cells and non-Hodgkin's lymphoma (NHL), which presents a heterogeneous group of diseases, and depending on the growth rate and the course of the disease, they can be indolent (slow-growing) and aggressive (fast-growing). Follicular lymphoma (FL) is the most common indolent form of NHL, while diffuse large B-cell lymphoma (DLBCL) is the most common aggressive form. Case report. This paper presents a case of NHL, DLBCL, localized in the cervix, histo-pathologically diagnosed in a 35-year-old woman who, after a cervical biopsy, was patho-histologically diagnosed with mild dysplasia (CIN1 / L-SIL) of the cervical epithelium and, after that, an infection with Human Papilloma Virus (HPV), subtypes 16 and 31 was proven. The diagnosis of DLBCL was patho-histologically confirmed on a conical section of the vaginal portion of the uterus, after which the disease was treated with eight cycles of chemotherapy (HT) according to the RCHOP protocol. Conclusion. The coexistence of CIN1 / L-SIL and NHL is random and may overlook concomitant cervical lymphoma, which is usually localized subepithelially, if the biopsy is not adequately performed and if HPV serotyping is not performed.
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