ÖzetAmaç: Günümüzde, radyolojik görüntüleme yöntemlerinin kullanımındaki artış, bu yöntemleri kullanan sağlık personelinin daha fazla radyasyona maruz kalma riskini arttırmaktadır. Çalışmamızda sağlık çalışanlarında radyasyon güvenliği farkındalığı ve bu farkındalığa etki eden faktörler araştırılmış-tır. Gereç ve Yöntem: Tanımlayıcı olarak planlanan bu çalışmada dört faklı merkezde; Nükleer Tıp, Radyoloji ve Radyasyon Onkolojisi ünitelerinde çalı-şan sağlık personeline araştırmacılar tarafından hazırlanan anket soruları yö-neltildi. Bulgular: Çalışmaya 4 farklı merkezden toplam 184 sağlık çalışanı dahil edildi. Katılımcıların sağlık görevlerine bağlı olarak, kurşun yelek kullanı-mı ve güvenliği açısından anlamlı bir fark saptandı (p<0.001, p:0.013). Dozimetre kullanımı ve katılımcıların görevleri arasında anlamlı ilişki tespit edildi (p:0.006). Katılımcıların görevleri ve radyasyon eğitimi açısından anlamlı ilişki vardı (p<0.001). Tartışma: Radyasyona maruz kalan sağlık personelinin daha kaliteli hizmet verebilmesi için personel radyasyondan nasıl korunacağını öğ-renmelidir. Radyasyon güvenlik komiteleri aktif şekilde çalışmalı, çalışanlara radyasyon eğitimi vermeli, doktorların bu eğitime katılmalarını sağlamalıdır. Anahtar KelimelerRadyasyon; Güvenlik; Farkındalık; Sağlık Çalışanları Abstract Aim: The increase in the usage of radiologic imaging methods today increases the risk of medical staff to be exposed to more radiation. In our study, the radiation safety awareness of medical staff and factors affecting this awareness were examined. Material and Method: In this study planned as descriptive, the medical staffs, who work in nuclear medicine, radiology and radiation oncology departments at four different centers, were asked survey questions prepared by researchers. Results: A total of 184 medical staff was involved in the study from 4 different centers. There was significant difference determined regarding the usage and safety of lead vest related to the duties of attendants (p<0.001, p:0.013). There was a significant relation determined between dosimeter usage and the duties of attendants (p:0.006). There were a significant relation between the duties of attendants and radiation training (p<0.001). Discussion: In order for the medical staff exposed to radiation to give more quality service, the staff should learn how to protect from radiation. Radiation safety committees should work actively, give radiation training to the staff, and provide that doctors also participate in these trainings.
Objectives: The objective of our study was to assess the prognostic significance of the Pan-Immune-Inflammation Value (PIV) before concurrent chemoradiation (C-CRT) and prophylactic cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer (SCLC). Methods: The medical records of LS-SCLC patients who underwent C-CRT and PCI between January 2010 and December 2021 were retrospectively analyzed. PIV values were calculated using the peripheral blood samples obtained within the past 7 days before the initiation of treatment: PIV = [neutrophils × platelets × monocytes] ÷ lymphocytes. Using receiver operating characteristic (ROC) curve analysis, the optimal pretreatment PIV cutoff values that can partition the study population into two groups with substantially distinct progression-free survival (PFS) and overall survival (OS) outcomes were determined. The relationship between PIV values and OS outcomes was the primary outcome measure. Results: Eighty-nine eligible patients were divided into two PIV groups at an optimal cutoff of 417 [Area under curve (AUC): 73.2%; sensitivity: 70.4%; specificity: 66.7%]: Group 1: PIV < 417 ( N = 36) and Group 2: PIV ≥ 417 ( N = 53). Comparative analyses revealed that patients with PIV < 417 had significantly longer OS (25.0 vs 14.0 months, p < .001) and PFS (18.0 vs 8.9 months, p = .004) compared to patients with PIV ≥ 417. The outcomes of the multivariate analysis have verified the independent significance of pretreatment PIV concerning PFS ( p < .001) and OS ( p < .001) outcomes. Conclusion: The findings of this retrospective study indicate that the pretreatment PIV is a reliable and independent prognostic biomarker for patients with LS-SCLC who were treated with C-CRT and PCI.
Objective The most common primary malignant tumors of the lung are squamous cell carcinoma, small cell carcinoma and adenocarcinoma. However, some rare malignant primary lung tumors can also affect the lung and cause difficulties in diagnosis and treatment. Conventional imaging methods do not help the diagnosis in most cases, and moreover, preoperative tissue samples may fail to establish a diagnosis. In cases with endobronchial lesions, small samples or lack of transthoracic biopsy in central tumors without endobronchial lesions can make diagnosis difficult. The definitive diagnosis can only be made after larger examinations with larger tissue samples taken after the operation. In addition, failure to differentiate benign- malignant in frozen examination may negatively affect the resection of the surgeon. It can cause incomplete or unnecessary resection. The aim of this study was to evaluate the clinical radiological and histopathological features of these tumors, which have been rarely reported in the literature, and to contribute to the diagnosis and treatment of these tumors. Material and Methods The study included 10 patients with rare malignant primary lung tumor who were operated on in our clinic between 2010 and 2019. All patients were retrospectively evaluated in respect of age, gender, symptoms, preoperative imaging methods and invasive diagnostic methods. Tumor localization, tumor size, type of surgical operation and survival were recorded. Results The 10 patients included in the study comprised 6 males and 4 females. Postoperative histopathological diagnoses of the patients were reported as 2 carcinosarcomas, 2 large cell carcinomas, 2 epithelioid hemangioendothelioma, 1 glomangiosarcoma, 1 primary pulmonary leiomyosarcoma, 1 mucoepidermoid carcinoma, and 1 synovial sarcoma. Conclusion It can be difficult to diagnose in rare primary malignant lung tumors by preoperative imaging and preoperative invasive diagnostic methods. CT-guided fine needle biopsy and tru-cut biopsy, endobronchial biopsy and frozen samples performed before surgery may be insufficient in diagnosis, which may mislead the surgeon about lung resection.
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